Literature DB >> 59797

Measurement of diphenylhydantoin and phenobarbital by enzyme immunoassay and gas-liquid chromatography.

D Schmidt.   

Abstract

A new enzyme-multiplied immunoassay technique (EMIT) was compared with Kupferberg's gas-liquid chromatography (GLC) for the determination of diphenylhydantoin and phenobarbital. 116 plasma samples of patients with epilepsy were examined simultaneously by EMIT and GLC. The precision of repeated determinations was similar for both procedures. There was good agreement between the EMIT and GLC results. The rapid and precise analysis, made possible by the EMIT system, is useful for the treatment of epilepsies.

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Year:  1976        PMID: 59797     DOI: 10.1007/bf00316338

Source DB:  PubMed          Journal:  J Neurol        ISSN: 0340-5354            Impact factor:   4.849


  4 in total

Review 1.  Usefulness of blood levels of antiepileptic drugs.

Authors:  H Kutt; J K Penry
Journal:  Arch Neurol       Date:  1974-11

2.  "Homogeneous" enzyme immunoassay. A new immunochemical technique.

Authors:  K E Rubenstein; R S Schneider; E F Ullman
Journal:  Biochem Biophys Res Commun       Date:  1972-05-26       Impact factor: 3.575

3.  Quantitative estimation of diphenylhydantoin, primidone and phenobarbital in plasma by gas-liquid chromatography.

Authors:  H J Kupferberg
Journal:  Clin Chim Acta       Date:  1970-08       Impact factor: 3.786

4.  Diphenylhydantoin, phenobarbital, and primidone in saliva, plasma, and cerebrospinal fluid.

Authors:  D Schmidt; J Kupferberg
Journal:  Epilepsia       Date:  1975-12       Impact factor: 5.864

  4 in total
  1 in total

1.  [Selected clinical aspects of routine monitoring of anticonvulsant concentrations in serum (author's transl)].

Authors:  R Heipertz; H Pilz; K Eickhoff; D Seidel
Journal:  Arch Psychiatr Nervenkr (1970)       Date:  1977-12-28
  1 in total

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