| Literature DB >> 59783 |
W A Hook, E Schiffmann, S Aswanikumar, R P Siraganian.
Abstract
Certain formyl dipeptides and tripeptides containing methionine released histamine from human basophils at concentrations of 10(-4) to 10(-7) M. However, N-formyl amino acids did not release histamine. Tripeptides, in general, were more active than dipeptides. An acyl group was required for histamine release although an N-terminal position for Met was not essential. Histamine release from human basophils by these peptides correlated well with their chemotactic activity for rabbit leukocytes.Entities:
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Year: 1976 PMID： 59783
Source DB: PubMed Journal: J Immunol ISSN： 0022-1767 Impact factor: 5.422