Literature DB >> 597244

Origins of blood acetate in the rat.

B M Buckley, D H Williamson.   

Abstract

A novel enzymimc cycling assay for the determination of acetate in biological material is described. Measurements of the acetate concentration in blood and liver samples from rats of various ages and nutritional states with this assay are reported. The contribution of the intestine, the liver and the rest of the body to maintaining the concentration of acetate in the circulation is examined. Evidence is presented that the gut flora constitute the main source of acetate in blood of fed adult rats, though endogenous production of acetate is of significance in other situations. The streptozotocin-diabetic rat has an elevated blood acetate concentration.

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Year:  1977        PMID： 597244      PMCID： PMC1165038          DOI： 10.1042/bj1660539

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  22 in total

1.  [A simple technic for extremely rapid freezing of large pieces of tissue].

Authors:  A WOLLENBERGER; O RISTAU; G SCHOFFA
Journal:  Pflugers Arch Gesamte Physiol Menschen Tiere       Date:  1960

2.  Enzymatic phosphorylation of acetate.

Authors:  I A ROSE; M GRUNBERG-MANAGO; S R KOREY; S OCHOA
Journal:  J Biol Chem       Date:  1954-12       Impact factor: 5.157

3.  Metabolism of ketonic acids in animal tissues.

Authors:  H A Krebs; W A Johnson
Journal:  Biochem J       Date:  1937-04       Impact factor: 3.857

4.  The measurement of pyridine nucleotides by enzymatic cycling.

Authors:  O H LOWRY; J V PASSONNEAU; D W SCHULZ; M K ROCK
Journal:  J Biol Chem       Date:  1961-10       Impact factor: 5.157

5.  Pyruvate oxidation system of heart muscle.

Authors:  S KORKES; A DEL CAMPILLO; S OCHOA
Journal:  J Biol Chem       Date:  1952-04       Impact factor: 5.157

6.  The pyruvate-oxidase system in brain and the tricarboxylic acid cycle.

Authors:  R V COXON; C LIEBECQ; R A PETERS
Journal:  Biochem J       Date:  1949       Impact factor: 3.857

7.  Production and utilization of acetate in mammals.

Authors:  S E Knowles; I G Jarrett; O H Filsell; F J Ballard
Journal:  Biochem J       Date:  1974-08       Impact factor: 3.857

8.  CITRATE AND THE CONVERSION OF CARBOHYDRATE INTO FAT. THE ACTIVITIES OF CITRATE-CLEAVAGE ENZYME AND ACETATE THIOKINASE IN LIVERS OF STARVED AND RE-FED RATS.

Authors:  M S KORNACKER; J M LOWENSTEIN
Journal:  Biochem J       Date:  1965-01       Impact factor: 3.857

9.  CITRATE AND THE CONVERSION OF CARBOHYDATE INTO FAT. ACTIVITIES OF CITRATE-CLEAVAGE ENZYME AND ACETATE THIOKINASE IN LIVERS OF NORMAL AND DIABETIC RATS.

Authors:  M S KORNACKER; J M LOWENSTEIN
Journal:  Biochem J       Date:  1965-06       Impact factor: 3.857

10.  Determination of volatile fatty acids in plasma after ethanolic extraction.

Authors:  C Remesy; C Demigne
Journal:  Biochem J       Date:  1974-07       Impact factor: 3.857
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  31 in total

Review 1.  The acetate switch.

Authors:  Alan J Wolfe
Journal:  Microbiol Mol Biol Rev       Date:  2005-03       Impact factor: 11.056

2.  Sirtuins: a conserved key unlocking AceCS activity.

Authors:  Brian J North; David A Sinclair
Journal:  Trends Biochem Sci       Date:  2006-12-01       Impact factor: 13.807

3.  Measurement of the rates of acetyl-CoA hydrolysis and synthesis from acetate in rat hepatocytes and the role of these fluxes in substrate cycling.

Authors:  B Crabtree; M J Gordon; S L Christie
Journal:  Biochem J       Date:  1990-08-15       Impact factor: 3.857

4.  Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes.

Authors:  Cong Tang; Kashan Ahmed; Andreas Gille; Shun Lu; Hermann-Josef Gröne; Sorin Tunaru; Stefan Offermanns
Journal:  Nat Med       Date:  2015-01-12       Impact factor: 53.440

5.  Measurement of the rate of substrate cycling between acetate and acetyl-CoA in sheep muscle in vivo. Effects of infusion of acetate.

Authors:  B Crabtree; S A Marr; S E Anderson; J C MacRae
Journal:  Biochem J       Date:  1987-05-01       Impact factor: 3.857

6.  Effects of short-term insulin deficiency on lipogenesis and cholesterol synthesis in rat small intestine and liver in vivo.

Authors:  D H Williamson; V Ilic; J Hughes
Journal:  Biochem J       Date:  1985-10-01       Impact factor: 3.857

7.  Compartmentation of acetyl CoA studied by analysis of tricarboxylic acid cycle acids and 3-hydroxybutyrate in bile of rats given [2,2,2-2H3]ethanol.

Authors:  C Norsten; T Cronholm
Journal:  Biochem J       Date:  1990-01-15       Impact factor: 3.857

8.  Substrate and inhibitor specificity of monocarboxylate transport into heart cells and erythrocytes. Further evidence for the existence of two distinct carriers.

Authors:  R C Poole; S L Cranmer; A P Halestrap; A J Levi
Journal:  Biochem J       Date:  1990-08-01       Impact factor: 3.857

9.  Competition between acetate and oleate for the formation of malonyl-CoA and mitochondrial acetyl-CoA in the perfused rat heart.

Authors:  Fang Bian; Takhar Kasumov; Kathryn A Jobbins; Paul E Minkler; Vernon E Anderson; Janos Kerner; Charles L Hoppel; Henri Brunengraber
Journal:  J Mol Cell Cardiol       Date:  2006-10-03       Impact factor: 5.000

10.  Purine biosynthesis de novo in rat skeletal muscle.

Authors:  T G Sheehan; E R Tully
Journal:  Biochem J       Date:  1983-12-15       Impact factor: 3.857
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