Literature DB >> 5967902

Metabolic studies of allopurinol, an inhibitor of xanthine oxidase.

G B Elion, A Kovensky, G H Hitchings.   

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Year:  1966        PMID: 5967902     DOI: 10.1016/0006-2952(66)90163-8

Source DB:  PubMed          Journal:  Biochem Pharmacol        ISSN: 0006-2952            Impact factor:   5.858


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  58 in total

Review 1.  Critical compilation of terminal half-lives, percent excreted unchanged, and changes of half-life in renal and hepatic dysfunction for studies in humans with references.

Authors:  L A Pagliaro; L Z Benet
Journal:  J Pharmacokinet Biopharm       Date:  1975-10

2.  Stimulation of peroxidative reactions by a high dose of allopurinol in the rat myocardium.

Authors:  F Boucher; C Coudray; A Favier; J de Leiris
Journal:  Cardiovasc Drugs Ther       Date:  1992-10       Impact factor: 3.727

3.  IBD: Switching metabolism-can two drugs be better than one?

Authors:  Miles P Sparrow
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2010-08       Impact factor: 46.802

4.  Nobel lecture in physiology or medicine--1988. The purine path to chemotherapy.

Authors:  G B Elion
Journal:  In Vitro Cell Dev Biol       Date:  1989-04

5.  Absence of chromosome damage in human lymphocytes exposed to allopurinol and oxipurinol.

Authors:  A C Stevenson; S R Silcock; J T Scott
Journal:  Ann Rheum Dis       Date:  1976-04       Impact factor: 19.103

6.  Why do most human liver cytosol preparations lack xanthine oxidase activity?

Authors:  John T Barr; Kanika V Choughule; Sahadev Nepal; Timothy Wong; Amarjit S Chaudhry; Carolyn A Joswig-Jones; Michael Zientek; Stephen C Strom; Erin G Schuetz; Kenneth E Thummel; Jeffrey P Jones
Journal:  Drug Metab Dispos       Date:  2014-01-15       Impact factor: 3.922

Review 7.  Clinical pharmacokinetics of allopurinol.

Authors:  G A Murrell; W G Rapeport
Journal:  Clin Pharmacokinet       Date:  1986 Sep-Oct       Impact factor: 6.447

8.  Effect of enzymatically generated reactive oxygen metabolites on the cyclic nucleotide content in isolated rat glomeruli.

Authors:  S V Shah
Journal:  J Clin Invest       Date:  1984-08       Impact factor: 14.808

Review 9.  Pharmacologically active drug metabolites: therapeutic and toxic activities, plasma and urine data in man, accumulation in renal failure.

Authors:  D E Drayer
Journal:  Clin Pharmacokinet       Date:  1976 Nov-Dec       Impact factor: 6.447

10.  Antileishmanial effect of allopurinol.

Authors:  M A Pfaller; J J Marr
Journal:  Antimicrob Agents Chemother       Date:  1974-05       Impact factor: 5.191

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