Collection of urine from each kidney in the rabbit without ureteral cannulation.

Collection of urine in rabbits by conventional methods such as catheterization of ureters or bladder with polyethylene tubing or Foley cannulas is hampered by the occurrence of hematuria or obstruction of urine flow, or both. These problems were solved by placing in the bladder a stainless steel device with a horizontal round disk attached to an eliptic vertical septum. The vertical septum divides the bladder into two compartments in such a way as to allow the collection of urine from each kidney. Studies show that this intrabladder devide can be satisfactorily used in acute experiments in anesthetized or conscious rabbits for periods up to 5-6 h.