Literature DB >> 594380

Termination of early pregnancy by ONO-802 (16,16-dimethyl-trans-delta2-PGE1 methyl ester).

S Takagi, H Sakata, T Yoshida, S Nakazawa, K T Fujii, Y Tominaga, Y Iwasa, T Ninagawa, T Hiroshima, Y Tomida, K Itoh, R Matsukawa.   

Abstract

ONO-802 was infused into the uterine cavity for the termination of early pregnancy in 45 healthy volunteers. Forty two (93%) of the 45 cases had complete abortions and two had incomplete abortions. Nine (20%) of the 45 volunteers complained of nausea, 7 (16%) vomited and 5 (11%) complained of abdominal pain. Neither diarrhea nor weakness was observed. These results suggest that ONO-802 is more acceptable for the termination of early pregnancy than is PGF2alpha.

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Year:  1977        PMID: 594380     DOI: 10.1016/0090-6980(77)90208-8

Source DB:  PubMed          Journal:  Prostaglandins        ISSN: 0090-6980


  1 in total

1.  Prostaglandin regulation of the content of sex hormone receptors in human decidual tissue.

Authors:  N A Yudaev; M K Asribekova; S K Karpova; L E Murashko
Journal:  Neurosci Behav Physiol       Date:  1981 Sep-Oct
  1 in total

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