Literature DB >> 5941341

Studies on flavonoid metabolism. Metabolism of flavone in the guinea pig.

N P Das, L A Griffiths.   

Abstract

1. The metabolism of flavone has been studied in the guinea pig; after administration of the compound either orally or intraperitoneally, 4'-hydroxyflavone is excreted in the urine. 2. Small amounts of 3',4'-dihydroxyflavone were also detected in the urine after oral administration of flavone. 3. Hydroxyflavone formation is not suppressed by administering high doses of the antibacterial compounds aureomycin and phthaloylsulphathiazole. 4. Although salicylic acid appeared in trace quantities in the urine after administration of flavone, no other aromatic acid metabolites of flavone were detected.

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Year:  1966        PMID： 5941341      PMCID： PMC1264868          DOI： 10.1042/bj0980488

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  7 in total

1.  m-Hydroxyphenylpropionic acid, a major urinary metabolite of catechin in the rat.

Authors:  L A GRIFFITHS
Journal:  Nature       Date:  1962-06-02       Impact factor: 49.962

2.  The metabolism and acid degradation of quercetin.

Authors:  M S MASRI; A N BOOTH; F DE EDS
Journal:  Arch Biochem Biophys       Date:  1959-11       Impact factor: 4.013

3.  [Fluorescence test in the paper chromatography of aliphatic acids].

Authors:  M PESEZ; J FERRERO
Journal:  Bull Soc Chim Biol (Paris)       Date:  1957-02-20

4.  Metabolic fate of hesperidin, eriodictyol, homoeridictyol, and diosmin.

Authors:  A N BOOTH; F T JONES; F DeEDS
Journal:  J Biol Chem       Date:  1958-02       Impact factor: 5.157

5.  Metabolic and glucosuria studies on naringin and phloridzin.

Authors:  A N BOOTH; F T JONES; F DEEDS
Journal:  J Biol Chem       Date:  1958-08       Impact factor: 5.157

6.  The metabolic fate of rutin and quercetin in the animal body.

Authors:  A N BOOTH; F DEEDS; F T JONES; C W MURRAY
Journal:  J Biol Chem       Date:  1956-11       Impact factor: 5.157

7.  Studies on flavonoid metabolism. Identification of the metabolities of (+)-catechin in rat urine.

Authors:  L A Griffiths
Journal:  Biochem J       Date:  1964-07       Impact factor: 3.857
  7 in total
  7 in total

1.  Metabolism of myricetin and related compounds in the rat. Metabolite formation in vivo and by the intestinal microflora in vitro.

Authors:  L A Griffiths; G E Smith
Journal:  Biochem J       Date:  1972-11       Impact factor: 3.857

2.  Identification of flavanone metabolites in rat urine by combined gas-liquid chromatography and mass spectrometry.

Authors:  N P Das; K N Scott; J H Duncan
Journal:  Biochem J       Date:  1973-12       Impact factor: 3.857

3.  Studies on flavonoid metabolism. Metabolism of (+)-catechin in the guinea pig.

Authors:  N P Das; L A Griffiths
Journal:  Biochem J       Date:  1968-12       Impact factor: 3.857

4.  Studies on flavonoid metabolism. Biliary and urinary excretion of metabolites of (+)-(U- 14 C)catechin.

Authors:  N P Das; S P Sothy
Journal:  Biochem J       Date:  1971-11       Impact factor: 3.857

5.  Metabolism of apigenin and related compounds in the rat. Metabolite formation in vivo and by the intestinal microflora in vitro.

Authors:  L A Griffiths; G E Smith
Journal:  Biochem J       Date:  1972-07       Impact factor: 3.857

6.  Studies on flavonoid metabolism. Metabolism of (+)-[14C] catechin in the rat and guinea pig.

Authors:  N P Das; L A Griffiths
Journal:  Biochem J       Date:  1969-12       Impact factor: 3.857

7.  Roles of cytochrome P450 2A6 in the oxidation of flavone, 4'-hydroxyflavone, and 4'-, 3'-, and 2'-methoxyflavones by human liver microsomes.

Authors:  Haruna Nagayoshi; Norie Murayama; Shigeo Takenaka; Vitchan Kim; Donghak Kim; Masayuki Komori; Hiroshi Yamazaki; F Peter Guengerich; Tsutomu Shimada
Journal:  Xenobiotica       Date:  2021-08-04       Impact factor: 1.908
  7 in total

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