Literature DB >> 593904

[Automated method of determining blood circulation time in nuclear medicine cardiology].

W H Knapp, J Doll.   

Abstract

In this paper a method of computer-assisted evaluation of circulation times using a scintillation camera is described. Eight segments of the central circulation are defined on a graphic display unit. Then the analysis of time-activity curves and the normalization of circulation times to hear rate is performed. The automatic analysis is based upon the hydrodynamic meaning of the first inflection point of a time-activity curve. The differences between inflection points are nearly identical with appearance time differences under the experimental conditions used in 131 cases. A mathematical model is presented to defined the conditions for this behaviour and to explain some deviations observed if time differences exceeded a certain value. It can be shown that the method described is largely independent of extraneous influences. It offers haemodynamically relevant parameters that correspond to the minimal cardiac transit times.

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Year:  1977        PMID: 593904

Source DB:  PubMed          Journal:  Nuklearmedizin        ISSN: 0029-5566            Impact factor:   1.379


  1 in total

1.  Calculation of residence time distributions of intravascular radioactive tracers in fields of external registration.

Authors:  W H Knapp; H J Lüdecke; J Doll
Journal:  Eur J Nucl Med       Date:  1979-12
  1 in total

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