Literature DB >> 5938779

Galactose conversion to D-xylulose: an alternate route of galactose metabolism.

P Cuatrecasas, S Segal.   

Abstract

Galactose dehydrogenase, a soluble enzyme of the mammalian liver, catalyzes the conversion of galactose to galactonic acid. This reaction, together with the subsequent formation of 3-ketogalactonic acid which can be decarboxylated to yield d-xylulose, is a newly discovered pathway for the metabolism of galactosee. This pathway may account for the oxidation of galactose observed in pathients with galactosemia.

Entities:  

Mesh：

Substances：

Year:  1966        PMID： 5938779     DOI： 10.1126/science.153.3735.549

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  15 in total

1.  Komrower Lecture. Galactosaemia today: the enigma and the challenge.

Authors:  S Segal
Journal:  J Inherit Metab Dis       Date:  1998-08       Impact factor: 4.982

2.  Contamination of commercially available intermediates of the glycolytic pathway.

Authors:  H Niessner; E Beutler
Journal:  Experientia       Date:  1973-03-15

3.  UDP-glucose: alpha-D-galactose-1-phosphate uridylytransferase activity in cultured human fibroblasts.

Authors:  J D Russell; R DeMars
Journal:  Biochem Genet       Date:  1967-06       Impact factor: 1.890

Review 4.  Classical galactosaemia revisited.

Authors:  Annet M Bosch
Journal:  J Inherit Metab Dis       Date:  2006-07-11       Impact factor: 4.982

5.  Oxidation of galactose by galactose-1-phosphate uridyltransferase-deficient lymphoblasts.

Authors:  C Yager; J Gibson; B States; L J Elsas; S Segal
Journal:  J Inherit Metab Dis       Date:  2001-08       Impact factor: 4.982

6.  Renal excretion of galactose and galactitol in patients with classical galactosaemia, obligate heterozygous parents and healthy subjects.

Authors:  P Schadewaldt; S Killius; L Kamalanathan; H W Hammen; K Strassburger; U Wendel
Journal:  J Inherit Metab Dis       Date:  2003       Impact factor: 4.982

7.  Transport and metabolism of galactose in rat kidney cortex.

Authors:  P D McNamara; S Segal
Journal:  Biochem J       Date:  1972-10       Impact factor: 3.857

8.  Galactose metabolism in transferase-deficient galactosaemic and normal long-term lymphoid cell lines.

Authors:  N G Beratis; L Wilbur
Journal:  J Inherit Metab Dis       Date:  1987       Impact factor: 4.982

Review 9.  Galactosemia unsolved.

Authors:  S Segal
Journal:  Eur J Pediatr       Date:  1995       Impact factor: 3.183

10.  The prevalence and clinical study of galactosemia disease in a pilot screening program of neonates, southern iran.

Authors:  S Senemar; Ah Ganjekarimi; S Senemar; B Tarami; M Bazrgar
Journal:  Iran J Public Health       Date:  2011-12-31       Impact factor: 1.429
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.