Literature DB >> 59377

Chemical mediators of anaphylaxis (histamine, 5-HT, and SRS-A) released from horse lung and leukocytes in vitro.

J F Burka, T R Deline, M C Holroyde, P Eyre.   

Abstract

Horses were sensitized to bovine plasma in Freund's complete adjuvant. Leukocytes, separated from venous blood, yielded histamine upon incubation with bovine plasma. Ioslated lung fragments incubated with bovine plasma liberated histamine and 5-HT, but not SRS-A. Pulmonary veins obtained from the same animals contracted to histamine, 5-HT and to antigen (Schultz-Dale reaction). Histamine and 5-HT probably contribute to immediate-type hypersensitivity in horses whereas the role of SRS-A is not proved.

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Year:  1976        PMID： 59377

Source DB:  PubMed          Journal:  Res Commun Chem Pathol Pharmacol        ISSN： 0034-5164


  8 in total

Review 1.  Pharmacological studies of pulmonary anaphylaxis in vitro: a review.

Authors:  P O Ogunbiyi; P Eyre
Journal:  Agents Actions       Date:  1985-12

Review 2.  The Schultz-Dale reaction: a review.

Authors:  N Chand; P Eyre
Journal:  Agents Actions       Date:  1978-04

3.  A reagin-like antibody in horse serum. II. Anti-human IgE induced reversed cutaneous anaphylaxis-like responses in horse skin.

Authors:  A G Matthews; P Imlah; E A McPherson
Journal:  Vet Res Commun       Date:  1983-03       Impact factor: 2.459

Review 4.  Auto-modulation of release of pharmacological mediators of immediate (type I) hypersensitivity. A review.

Authors:  M C Holroyde; J F Burka; P Eyre
Journal:  Agents Actions       Date:  1977-10

5.  Effects of aerosolized histamine and carbachol in the conscious horse.

Authors:  K B Mirbahar; W N McDonell; W Bignell; P Eyre
Journal:  Can J Comp Med       Date:  1985-04

6.  Anaphylactic contraction of pulmonary blood vessels of chicken.

Authors:  N Chand; P Eyre
Journal:  Br J Pharmacol       Date:  1977-01       Impact factor: 8.739

7.  Spasmolytic action of histamine in airway smooth muscle of horse.

Authors:  N Chand; P Eyre
Journal:  Agents Actions       Date:  1978-04

8.  Immunological release of histamine and slow-reacting substance in domestic fowl.

Authors:  N Chand; P Eyre
Journal:  Can J Comp Med       Date:  1978-10
  8 in total

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