Literature DB >> 5934341

Immunoglobulin structure: variation in the sequence of Bence Jones proteins.

K Titani, E Whitley, F W Putnam.   

Abstract

Analysis of the amino acid sequence of one Bence Jones protein is almost comtplete. Many points of interchange occur in the amino terminal. portion of the molecule relative to partial-sequence data for other proteins. Most, but not all, are, compartible with one-step mutations. Such structural variation in immunoglobulin light chains may result from many related genes.

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Year:  1966        PMID： 5934341     DOI： 10.1126/science.152.3728.1513

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  18 in total

1.  Somatic recombination of duplicated genes: an hypothesis on the origin of antibody diversity.

Authors:  G M Edelman; J A Gally
Journal:  Proc Natl Acad Sci U S A       Date:  1967-02       Impact factor: 11.205

2.  The evolutionary origins of the immunoglobulins.

Authors:  R L Hill; R Delaney; R E Fellows; H E Lebovitz
Journal:  Proc Natl Acad Sci U S A       Date:  1966-12       Impact factor: 11.205

3.  Immunoglobulin kappa-chains. Comparative sequences in selected stretches of Bence-Jones proteins.

Authors:  C Milstein
Journal:  Biochem J       Date:  1966-11       Impact factor: 3.857

4.  Electrophoretic analysis of antibody produced by single cells.

Authors:  J J Marchalonis; G J Nossal
Journal:  Proc Natl Acad Sci U S A       Date:  1968-11       Impact factor: 11.205

5.  N-terminal sequences of heavy and light chains of leopard shark immunoglobulins: evolutionary implications.

Authors:  A A Suran; B W Papermaster
Journal:  Proc Natl Acad Sci U S A       Date:  1967-10       Impact factor: 11.205

6.  Specific dimerization of the light chains of human immunoglobulin.

Authors:  G T Stevenson; D Straus
Journal:  Biochem J       Date:  1968-07       Impact factor: 3.857

7.  [Molecular basis of antibody formation].

Authors:  N Hilschmann
Journal:  Naturwissenschaften       Date:  1969-04

Review 8.  [Genetic mechanisms of antibody formation].

Authors:  O Wetter; C G Schmidt
Journal:  Klin Wochenschr       Date:  1968-04-15

9.  On the homologous relationship between the variable and the constant parts of immunoglobulins.

Authors:  J Urbain
Journal:  Biochem Genet       Date:  1972-04       Impact factor: 1.890

10.  The paucity of species-specific amino acid residues in the variable regions of human and mouse Bence-Jones proteins and its evolutionary and genetic implications.

Authors:  E A Kabat
Journal:  Proc Natl Acad Sci U S A       Date:  1967-05       Impact factor: 11.205
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