| Literature DB >> 593350 |
Abstract
An evolutionary view of ageing suggests that mortality may be due to an energy-saving strategy of reduced error regulation in somatic cells. This supports Orgel's 'error catastrophe' hypothesis and offers a new basis for the study of normal and abnormal ageing syndromes and of apparently immortal transformed cell lines.Mesh：
Year: 1977 PMID： 593350 DOI： 10.1038/270301a0
Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962