Literature DB >> 592959

[Management of early breast cancer (author's transl)].

W D George.   

Abstract

The results of clinical trials for early cancer of the breast were assessed in terms of survival, morbidity, and the rate of local recurrance. Simple mastectomy appeared to be the operation of choice because survival following this procedure was equal to that following more radical operations, but the morbidity was less. Partial mastectomy was found to be an unsatisfactory method of treatment. Simple mastectomy should be combined with removal of the lower axillary nodes to allow accurate staging of the disease. Postoperative radiotherapy did not influence survival, but did increase morbidity. It may be best to restrict its use to the treatment of local recurrance. Improvement in survival figures may be seen by use of adjuvant chemotherapy, or by more widespread use of screening programmes.

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Year:  1977        PMID: 592959     DOI: 10.1007/bf01305456

Source DB:  PubMed          Journal:  Langenbecks Arch Chir        ISSN: 0023-8236


  8 in total

1.  Screening for breast cancer.

Authors:  W D George; E N Gleave; P C England; M C Wilson; R A Sellwood; D Asbury; G Hartley; P G Barker; P Hobbs; J Wakefield
Journal:  Br Med J       Date:  1976-10-09

2.  The treatment of operable cancer of the breast: A clinical trial in the South-East region of Scotland.

Authors:  T Hamilton; A O Langlands; R J Prescott
Journal:  Br J Surg       Date:  1974-10       Impact factor: 6.939

3.  'Early' breast cancer: the Hammersmith trial. An interim report.

Authors:  J I Burn
Journal:  Br J Surg       Date:  1974-10       Impact factor: 6.939

4.  Skeletal metastases and mammary cancer.

Authors:  C S Galasko
Journal:  Ann R Coll Surg Engl       Date:  1972-01       Impact factor: 1.891

5.  1-Phenylalanine mustard (L-PAM) in the management of primary breast cancer. A report of early findings.

Authors:  B Fisher; P Carbone; S G Economou; R Frelick; A Glass; H Lerner; C Redmond; M Zelen; P Band; D L Katrych; N Wolmark; E R Fisher
Journal:  N Engl J Med       Date:  1975-01-16       Impact factor: 91.245

6.  Treatment of stage-II carcinoma of the female breast.

Authors:  D Brinkley; S L Haybittle
Journal:  Lancet       Date:  1966-08-06       Impact factor: 79.321

7.  Treatment of early breast cancer: a report after ten years of a clinical trial.

Authors:  H Atkins; J L Hayward; D J Klugman; A B Wayte
Journal:  Br Med J       Date:  1972-05-20

8.  Combination chemotherapy as an adjuvant treatment in operable breast cancer.

Authors:  G Bonadonna; E Brusamolino; P Valagussa; A Rossi; L Brugnatelli; C Brambilla; M De Lena; G Tancini; E Bajetta; R Musumeci; U Veronesi
Journal:  N Engl J Med       Date:  1976-02-19       Impact factor: 91.245

  8 in total

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