Literature DB >> 592329

Structure-activity studies on hallucinogenic amphetamines using molecular connectivity.

L B Kier, L H Hall.   

Abstract

A series of ring-substituted hallucinogenic amphetamines has been analyzed using molecular connectivity. A correlating equation has been found between potency and connectivity terms. The equation permits an interpretation of SAR. The equation is capable of predicting potency for amphetamines not in the list and mescalines and tryptamines.

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Year:  1977        PMID: 592329     DOI: 10.1021/jm00222a019

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


  3 in total

1.  Molecular connectivity of phenols and their toxicity to fish.

Authors:  L H Hall; L B Kier
Journal:  Bull Environ Contam Toxicol       Date:  1984-03       Impact factor: 2.151

2.  Structural influences and mechanisms of toxic effects of alcohols and their derivatives.

Authors:  L B Kier; L H Hall
Journal:  Bull Environ Contam Toxicol       Date:  1982-07       Impact factor: 2.151

3.  QSAR modeling of beta-lactam binding to human serum proteins.

Authors:  L Mark Hall; Lowell H Hall; Lemont B Kier
Journal:  J Comput Aided Mol Des       Date:  2003 Feb-Apr       Impact factor: 3.686

  3 in total

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