Literature DB >> 5921386

Rapid and marked inhibition of rat-liver RNA polymerase by aflatoxin B-1.

H V Gelboin, J S Wortham, R G Wilson, M Friedman, G N Wogan.   

Abstract

From 15 minutes to 2 hours after the administration of aflatoxin B(1) invivo there is a 35-to 70-percent inhibition of DNA-directed RNA synthesis. The inhibition was reversed 12 and 24 hours later.

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Year:  1966        PMID： 5921386     DOI： 10.1126/science.154.3753.1205

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  9 in total

Review 1.  Biological activities of mycotoxins.

Authors:  A W Hayes
Journal:  Mycopathologia       Date:  1978-12-18       Impact factor: 2.574

2.  [Significance of the aflatoxins].

Authors:  H Bösenberg
Journal:  Naturwissenschaften       Date:  1969-07

3.  Aflatoxin - induced alteration in the levels of membrane chemical of subcellular organelles isolated from excised, incubated glycine max, cv. "Essex" roots. I. Non-enriched organelles.

Authors:  J M Danley; S Staggers; S Walker; A Varner; G C Llewellyn; W V Dashek
Journal:  Mycopathologia       Date:  1981-06-05       Impact factor: 2.574

4.  Mutagenic activities of aflatoxin B 1 and G 1 in Neurospora crassa.

Authors:  T M Ong
Journal:  Mol Gen Genet       Date:  1971

5.  Effects of dioxane on RNA synthesis in the rat liver.

Authors:  R N Kurl; L Poellinger; J Lund; J A Gustafsson
Journal:  Arch Toxicol       Date:  1981-11       Impact factor: 5.153

6.  Effects of aflatoxin B 1 on human skin lipids metabolism--a site of action on 1- 14 C-acetate incorporation.

Authors:  W B Lo; H S Black
Journal:  Experientia       Date:  1972-11-15

7.  Hepatic megalocytosis in chronic lasiocarpine poisoning. Some functional studies.

Authors:  D Svoboda; J Reddy; S Bunyaratvej
Journal:  Am J Pathol       Date:  1971-11       Impact factor: 4.307

8.  Studies on the pathogenesis of liver necrosis by alpha-amanitin. Effect of alpha-amanitin on ribonucleic acid synthesis and on ribonucleic acid polymerase in mouse liver nuclei.

Authors:  F Stirpe; L Fiume
Journal:  Biochem J       Date:  1967-11       Impact factor: 3.857

9.  Alpha benzene hexachloride inhibition of aflatoxin B1-induced hepatocellular carcinoma. A preliminary report.

Authors:  S Angsubhakorn; N Bhamarapravati; K Romruen; S Sahaphong; W Thamavit
Journal:  Experientia       Date:  1978-08-15
  9 in total

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