| Literature DB >> 59188 |
A J Vogten, W H Summerskill, G L Gitnick, S W Schalm, J L Smith, B L Murphy, J E Maynard.
Abstract
Serial determinations of e antigen and e antibody were made in 20 patients with chronic active liver disease and hepatitis-B surface antigen (HBsAg) or antibody (anti-HBs). The presence of e antigen was associated with failure to clear HBsAg, produce anti-HBs, or respond to treatment with steroids. It is proposed that the presence of the e antigen is associated with impaired host immune responses to hepatitis-B virus infection and a poor prognosis.Entities:
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Year: 1976 PMID： 59188 DOI： 10.1016/s0140-6736(76)92849-x
Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321