Literature DB >> 5918718

"Copulation-reward site" in the posterior hypothalamus.

A R Caggiula, B G Hoebel.   

Abstract

Posterior hypothalamic selfstimulation of male rats, in which monopolar,platinum electrodes had been belaterally implanted, increased after systdmic injection of testosterone. constant stimulation to the same site elicited immediate copulation with estrous female rats. During constant stimulation males would press a bar to open a door for access to females. Even after ejaculation, males continued to open the door and to display sexual activity until stimulation terminated. Posterior hypothalamic stimulation is like normal sexual stimulation; it is rewarding, the reward varies with the amount of the sex hormone, and it elicits motivated copulation.

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Year:  1966        PMID: 5918718     DOI: 10.1126/science.153.3741.1284

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


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