Literature DB >> 5917092

Inherited variations of human serum alpha-1-antitrypsin.

F Kueppers, A G Bearn.   

Abstract

The normal serum alpha(1)-antitrypsin migrates as a three banded patternwhen separated electrophoretically in starch gel with a sodium acetateethylenediaminetetraacetic acid buffer of pH 4.95. The results obtained when certain inherited variants of the serum alpha(1)-antitrypsin are separated electrophoretically suggest that the previously described variations in the region preceding the albumin band represent inherited variations of the serum alpha(1)-antitrypsin.

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Year:  1966        PMID: 5917092     DOI: 10.1126/science.154.3747.407

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  9 in total

Review 1.  Antitrypsin and the liver.

Authors:  P W Brunt
Journal:  Gut       Date:  1974-07       Impact factor: 23.059

2.  Alpha 1-antitrypsin in serum and synovial fluid in rheumatoid arthritis.

Authors:  H A Swedlund; G G Hunder; G J Gleich
Journal:  Ann Rheum Dis       Date:  1974-03       Impact factor: 19.103

3.  Alloalbuminemia in two Brazilian populations: a possible new variant.

Authors:  F M Salzano; M Helena; L P Franco; M Ayres
Journal:  Am J Hum Genet       Date:  1974-01       Impact factor: 11.025

4.  Alpha 1 -antitrypsin levels and electrophoretic patterns of several deficient phenotypes.

Authors:  F Kueppers
Journal:  Humangenetik       Date:  1972

5.  Identification of the heterozygous state for the alpha-1-antitrypsin deficiency gene in man.

Authors:  F Kueppers
Journal:  Biochem Genet       Date:  1969-06       Impact factor: 1.890

6.  Gene frequencies of red cell adenosine deaminase, adenylate kinase, phosphoglucomutase, acid phosphatase and serum alpha-1-Antitrypsin (Pi) in a German population.

Authors:  H W Goedde; H G Benkmann; I Christ; S Singh; L Hirth
Journal:  Humangenetik       Date:  1970

Review 7.  Alpha-1-antitrypsin: physiology, genetics and pathology.

Authors:  F Kueppers
Journal:  Humangenetik       Date:  1971

8.  An inherited alpha-1-antitrypsin variant.

Authors:  F Kueppers; A G Bearn
Journal:  Humangenetik       Date:  1967-09-06

9.  Population genetics of alpha1-antitrypsin in the Netherlands. Description of a new electrophoretic variant.

Authors:  E C Klasen; C Franken; W S Volkers; L F Bernini
Journal:  Hum Genet       Date:  1977-07-26       Impact factor: 4.132

  9 in total

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