Literature DB >> 5914761

Purification and reconstitution of the periodic fibril and unit structure of human amyloid.

G G Glenner, H A Bladen.   

Abstract

Extraction with alkaline sodium glycinate of the periodic fibril and unit structure of human amyloid and subsequent acidification of the extract provided a method for the purification as well as for the reconstitution of the periodic rod and of the unit structure. Guanidine completely solubilized and irreversibly dissociated both the rod and the unit structure of the human amyloid fibril.

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Year:  1966        PMID: 5914761     DOI: 10.1126/science.154.3746.271

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  5 in total

1.  Pentosome--a new connective tissue component--is a subunit of amyloid P.

Authors:  S Inoue
Journal:  Cell Tissue Res       Date:  1991-03       Impact factor: 5.249

2.  The relationship of a serum protein, C1t, to a common nonfibrillar constituent of amyloid (P component) as revealed by immunohistochemical studies.

Authors:  A Katz; J Weicker-Thorne; R H Painter
Journal:  Am J Pathol       Date:  1977-09       Impact factor: 4.307

3.  Lymphocyte transformation in patients with amyloidosis.

Authors:  T Lehner; J S Cameron; R G Ward
Journal:  Clin Exp Immunol       Date:  1970-03       Impact factor: 4.330

4.  Reconstitution of amyloid fibrils from alkaline extracts.

Authors:  T Shirahama; A S Cohen
Journal:  J Cell Biol       Date:  1967-11       Impact factor: 10.539

Review 5.  Cerebrospinal Fluid Biomarkers in Alzheimer's Disease-From Brain Starch to Bench and Bedside.

Authors:  Matthias Pawlowski; Sven G Meuth; Thomas Duning
Journal:  Diagnostics (Basel)       Date:  2017-07-13
  5 in total

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