| Literature DB >> 5914761 |
Abstract
Extraction with alkaline sodium glycinate of the periodic fibril and unit structure of human amyloid and subsequent acidification of the extract provided a method for the purification as well as for the reconstitution of the periodic rod and of the unit structure. Guanidine completely solubilized and irreversibly dissociated both the rod and the unit structure of the human amyloid fibril.Entities:
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Year: 1966 PMID: 5914761 DOI: 10.1126/science.154.3746.271
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728