Literature DB >> 5911523

The choline acetyltransferase of human placenta.

D Morris.   

Abstract

1. Various methods for the extraction of choline acetyltransferase (acetyl-CoA-choline O-acetyltransferase, EC 2.3.1.6) from immature human placenta (18-28 weeks of gestation) are described. 2. The crude enzyme was found to be stable at -18 degrees and +4 degrees under a variety of conditions. 3. Purification methods, including ammonium sulphate fractionation, gel filtration on various grades of Sephadex and DEAE-Sephadex fractionation, have yielded a preparation of high specific activity.

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Year:  1966        PMID: 5911523      PMCID: PMC1264916          DOI: 10.1042/bj0980754

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  12 in total

1.  ACETYLCHOLINE AND CHOLINE ACETYLTRANSFERASE IN THE DIAPHRAGM OF THE RAT.

Authors:  C O HEBB; K KRNJEVIC; A SILVER
Journal:  J Physiol       Date:  1964-06       Impact factor: 5.182

2.  SEDIMENTATION BEHAVIOR AND MOLECULAR WEIGHT OF CHOLINE ACETYLTRANSFERASE.

Authors:  G BULL; A FEINSTEIN; D MORRIS
Journal:  Nature       Date:  1964-03-28       Impact factor: 49.962

3.  A COMPARISON OF THE N-ALKYL GROUP SPECIFICITY OF CHOLINE ACETYLTRANSFERASE FROM DIFFERENT SPECIES.

Authors:  B A HEMSWORTH; D MORRIS
Journal:  J Neurochem       Date:  1964-11       Impact factor: 5.372

4.  DETERMINATION OF MOLECULAR WEIGHTS AND FRICTIONAL RATIOS OF MACROMOLECULES IN IMPURE SYSTEMS: AGGREGATION OF UREASE.

Authors:  L M SIEGEL; K J MONTY
Journal:  Biochem Biophys Res Commun       Date:  1965-05-03       Impact factor: 3.575

5.  Choline acetylase in normal and denervated salivary glands.

Authors:  I NORDENFELT
Journal:  Q J Exp Physiol Cogn Med Sci       Date:  1963-01

6.  Biochemical evidence for the neural function of acetylcholine.

Authors:  C O HEBB
Journal:  Physiol Rev       Date:  1957-04       Impact factor: 37.312

7.  Highly purified choline acetylase.

Authors:  H KUMAGAI; S EBASHI
Journal:  Nature       Date:  1954-05-08       Impact factor: 49.962

8.  Choline esters in tissue extracts.

Authors:  H C Chang; J H Gaddum
Journal:  J Physiol       Date:  1933-10-06       Impact factor: 5.182

9.  Choline acetylase in the placenta of man and other species.

Authors:  C O Hebb; D Ratković
Journal:  J Physiol       Date:  1962-09       Impact factor: 5.182

10.  Properties and biological significance of choline acetylase.

Authors:  R B REISBERG
Journal:  Yale J Biol Med       Date:  1957-02
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  9 in total

1.  Some properties of choline acetyltransferase isolated from the electric organ ofTorpedo marmorata: Specificity for choline analogues and inhibition by certain amines and amino acids.

Authors:  R R Baker; M J Dowdall
Journal:  Neurochem Res       Date:  1976-04       Impact factor: 3.996

Review 2.  Molecular biology and neurobiology of choline acetyltransferase.

Authors:  P M Salvaterra
Journal:  Mol Neurobiol       Date:  1987       Impact factor: 5.590

3.  On the mechanism of action of choline acetyltransferase.

Authors:  S F Currier; H G Mautner
Journal:  Proc Natl Acad Sci U S A       Date:  1974-09       Impact factor: 11.205

4.  Isotopic exchange between acetylcholine and [Me-14C] choline catalysed by human placental choline acetyltransferase.

Authors:  D Morris; D S Grewaal
Journal:  Biochem J       Date:  1969-10       Impact factor: 3.857

5.  The use of choline acetyltransferase for measuring the synthesis of acetyl-coenzyme A and its release from brain mitochondria.

Authors:  S Tucek
Journal:  Biochem J       Date:  1967-09       Impact factor: 3.857

6.  Purification and immunochemical properties of choline acetyltransferase from human brain.

Authors:  J H Peng; P L McGeer; H Kimura; S C Sung; E G McGeer
Journal:  Neurochem Res       Date:  1980-09       Impact factor: 3.996

7.  The Coordinated Activities of nAChR and Wnt Signaling Regulate Intestinal Stem Cell Function in Mice.

Authors:  Toshio Takahashi; Akira Shiraishi; Jun Murata
Journal:  Int J Mol Sci       Date:  2018-03-05       Impact factor: 5.923

8.  Upregulating nonneuronal cholinergic activity decreases TNF release from lipopolysaccharide-stimulated RAW264.7 cells.

Authors:  Yi Lv; Sen Hu; Jiangyang Lu; Ning Dong; Qian Liu; Minghua Du; Huiping Zhang
Journal:  Mediators Inflamm       Date:  2014-03-09       Impact factor: 4.711

Review 9.  Acetylcholine From Tuft Cells: The Updated Insights Beyond Its Immune and Chemosensory Functions.

Authors:  Jun Pan; Leyi Zhang; Xuan Shao; Jian Huang
Journal:  Front Cell Dev Biol       Date:  2020-07-07
  9 in total

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