Literature DB >> 5909587

Tetraethylammonium and tetrodotoxin: effects on cochlear potentials.

Y Katsuki, K Yanagisawa, J Kanzaki.   

Abstract

Tetraethylammonium chloride, which is believed to decrease potassium conductance, and tetrodotoxin, which apparently decreases sodium conductance in nerve fibers, were introduced iontophoretically into the organ of Corti or the scala media of guinea pig cochlea. The former depressed the direct-current endocochlear potential and also the alternating-current cochlear microphonics (the receptor potential of the ear), but tetrodotoxin was ineffective except on the nerve impulses.

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Year:  1966        PMID: 5909587     DOI: 10.1126/science.151.3717.1544

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  7 in total

1.  Electrochemical aspects of cations in the cochlear hair cell of the chinchilla: a cellular model of the ion movement.

Authors:  K Ikeda; T Morizono
Journal:  Eur Arch Otorhinolaryngol       Date:  1990       Impact factor: 2.503

2.  A study of the electrochemistry and osmotic relationships of the cochlear fluids in the neonatal rat at the time of the development of the endocochlear potential.

Authors:  S K Bosher; R L Warren
Journal:  J Physiol       Date:  1971-02       Impact factor: 5.182

3.  Evidence that catecholamines are not the afferent transmitter in the cochlea.

Authors:  R Klinke; E F Evans
Journal:  Exp Brain Res       Date:  1977-06-27       Impact factor: 1.972

4.  The effects of intracochlear cyanide and tetrodotoxin on the properties of single cochlear nerve fibres in the cat.

Authors:  E F Evans; R Klinke
Journal:  J Physiol       Date:  1982-10       Impact factor: 5.182

5.  Permeability to potassium of the endolymph-perilymph barrier and its possible relation to hair cell function.

Authors:  T Konishi; A N Salt
Journal:  Exp Brain Res       Date:  1980       Impact factor: 1.972

Review 6.  Tetrodotoxin as a tool to elucidate sensory transduction mechanisms: the case for the arterial chemoreceptors of the carotid body.

Authors:  Asuncion Rocher; Ana Isabel Caceres; Ana Obeso; Constancio Gonzalez
Journal:  Mar Drugs       Date:  2011-12-15       Impact factor: 6.085

7.  A mechanism by which the hair cells of the inner ear transduce mechanical energy into a modulated train of action potentials.

Authors:  R Malcolm
Journal:  J Gen Physiol       Date:  1974-06       Impact factor: 4.086

  7 in total

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