Literature DB >> 590921

Decreased sensitivity to insulin in white adipose tissue from adrenalectomised rats.

S J Smith, E D Saggerson.   

Abstract

The ability of insulin to increase both [14C]-glucose incorporation into fatty acids and pyruvate dehydrogenase activity in incubated rat epididymal adipose tissues was considerably lessened after adrenalectomy. Insulin antagonism of adrenaline-stimulated lipolysis in isolated fat cells was abolished after adrenalectomy. Percentage stimulation of lipolysis above basal by adrenaline was not appreciably altered by adrenalectomy.

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Year:  1977        PMID: 590921     DOI: 10.1055/s-0028-1093503

Source DB:  PubMed          Journal:  Horm Metab Res        ISSN: 0018-5043            Impact factor:   2.936


  2 in total

1.  Alterations in response of rat white adipocytes to insulin, noradrenaline, corticotropin and glucagon after adrenalectomy. Correction of these changes by adenosine deaminase.

Authors:  B M Fernandez; E D Saggerson
Journal:  Biochem J       Date:  1978-07-15       Impact factor: 3.857

2.  Insulin binding and insulin action in rat fat cells after adrenalectomy.

Authors:  H Häring; C Calle; A Bug; R Renner; K D Hepp; W Kemmler
Journal:  Diabetologia       Date:  1980-10       Impact factor: 10.122

  2 in total

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