Literature DB >> 590242

Comparison of aldolase isozymes in placenta, HeLa cells, and human fibroblast cultures.

R Gliksman, N K Ghosh, R P Cox.   

Abstract

The aldolase specific activity of the human carcinoma cell line, HeLa, against fructose 1,6-diphosphate as substrate is 4- to 5-fold greater than the specific activity of diploid human fibroblast cultures derived from skin and lung. HeLa aldolase is isozyme is predominantly the A type and its substrate preferences resemble human placenta. These findings provide further support for the oncofetal enzyme consitution of HeLa cells.

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Year:  1977        PMID: 590242     DOI: 10.1159/000458828

Source DB:  PubMed          Journal:  Enzyme        ISSN: 0013-9432


  2 in total

1.  Complete amino acid sequence for human aldolase B derived from cDNA and genomic clones.

Authors:  W H Rottmann; D R Tolan; E E Penhoet
Journal:  Proc Natl Acad Sci U S A       Date:  1984-05       Impact factor: 11.205

2.  Comparative use of glucose and fructose in cultured fibroblasts from patients with hereditary fructose intolerance.

Authors:  F Lemonnier; B Delhotal-Landes; M Couturier; D Decimo; M Odiévre; M Gautier; A Lemonnier
Journal:  J Inherit Metab Dis       Date:  1987       Impact factor: 4.982

  2 in total

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