Literature DB >> 59012

Immunisation against hepatitis B in man.

P Maupas, A Goudeau, P Coursaget, J Drucker, P Bagros.   

Abstract

An inactivated vaccine against hepatitis B was prepared from blood-donor HBs antigen purified on immunoadsorbents. Its safety and efficacy were tested in chimpanzees. Vaccination was then applied in an attempt to protect patients and staff in a haemodialysis unit. The efficacy of the vaccine in man was assessed by observing humoral and cellular immune reactions and by comparing changes in HBs antigenaemia in vaccinated and non-vaccinated subjects. The results indicate that this vaccine protects against hepatitis B in the circumstances in which it was administered.

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Year:  1976        PMID: 59012     DOI: 10.1016/s0140-6736(76)93023-3

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  26 in total

1.  DNA vaccine for hepatitis B: evidence for immunogenicity in chimpanzees and comparison with other vaccines.

Authors:  H L Davis; M J McCluskie; J L Gerin; R H Purcell
Journal:  Proc Natl Acad Sci U S A       Date:  1996-07-09       Impact factor: 11.205

2.  Diseases of the alimentary system. Significance of persistent HBs antigenaemia.

Authors:  I L Woolf; R Williams
Journal:  Br Med J       Date:  1976-10-02

3.  Vaccine against hepatitis B--18 months prevention in a high risk setting.

Authors:  P Maupas; A Goudeau; P Coursaget; J Drucker; P Bagros; S Baudin; N Geslin
Journal:  Med Microbiol Immunol       Date:  1978-11-17       Impact factor: 3.402

Review 4.  Prophylactic vaccination against hepatitis B: achievements, challenges and perspectives.

Authors:  Wolfram H Gerlich
Journal:  Med Microbiol Immunol       Date:  2014-12-19       Impact factor: 3.402

Review 5.  Recent advances in the identification of hepatitis viruses.

Authors:  J L Dienstag; R H Purcell
Journal:  Postgrad Med J       Date:  1977-07       Impact factor: 2.401

6.  Proteins of hepatitis B surface antigen.

Authors:  J W Shih; J L Gerin
Journal:  J Virol       Date:  1977-01       Impact factor: 5.103

7.  Hepatitis B virus vaccine: identification of HBsAg/a and HBsAg/d but not HBsAg/y subtype antigenic determinants on a synthetic immunogenic peptide.

Authors:  A M Prince; H Ikram; T P Hopp
Journal:  Proc Natl Acad Sci U S A       Date:  1982-01       Impact factor: 11.205

8.  Hepatitis B vaccine: further studies in children with previously acquired hepatitis B surface antigenemia.

Authors:  F Barin; B Yvonnet; A Goudeau; P Coursaget; J P Chiron; F Denis; I D Mar
Journal:  Infect Immun       Date:  1983-07       Impact factor: 3.441

9.  Recombinant adenovirus induces antibody response to hepatitis B virus surface antigen in hamsters.

Authors:  J E Morin; M D Lubeck; J E Barton; A J Conley; A R Davis; P P Hung
Journal:  Proc Natl Acad Sci U S A       Date:  1987-07       Impact factor: 11.205

10.  Humoral and cellular immunity to hepatitis B virus-derived antigens: comparative activity of Freund complete adjuvant alum, and liposomes.

Authors:  Y Sanchez; I Ionescu-Matiu; G R Dreesman; W Kramp; H R Six; F B Hollinger; J L Melnick
Journal:  Infect Immun       Date:  1980-12       Impact factor: 3.441

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