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Literature DB >> 589868

An experimental comparison of radioactive labels with potential application to lymphocyte migration studies in patients.

Abstract

The suitability of two radionuclides (99mTc, 111In) for labelling lymphocytes have been evaluated in rats by comparison with a standard method using 51Cr. For the study of lymphocyte migration in patients labelling with 111In-labelled oxine is clearly the most promising because both in vivo and in vitro it remains associated with lymphocytes and the labelled cells migrate normally into lymphoid tissues. The physical characteristics of 111In are also favourable. Not only does 99mTc rapidly dissociate from lymphocytes but also it compromises their ability to recirculate from blood to lymph.

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Year: 1977 PMID： 589868 PMCID： PMC1541079

Source DB: PubMed Journal: Clin Exp Immunol ISSN： 0009-9104 Impact factor: 4.330

13 in total

1. [Drainage of the thoracic duct before transplantation in patients with chronic renal insufficiency].

Authors: J P Revillard; J Brochier; A Durix; J P Bernhardt; P A Bryon; J P Archimbaud; D Fries; J Traeger
Journal: Nouv Rev Fr Hematol Date: 1968 Sep-Oct

2. A lymph node weight assay for the graft-versus-host activity of rat lymphoid cells.

Authors: W L Ford; W Burr; M Simonsen
Journal: Transplantation Date: 1970-09 Impact factor: 4.939

3. Use of 99mTc as a radioisotopic label to study the migratory patterns of normal and neoplastic cells.

Authors: R F Barth; O Singla; G Y Gillespie
Journal: J Nucl Med Date: 1974-08 Impact factor: 10.057

4. Cytogenetic and scanning study of patients receiving intra-articular injections of gold-198 and yttrium-90.

Authors: A C Stevenson; J Bedford; G W Dolphin; R J Purrott; D C Lloyd; A G Hill; H F Hill; J M Gumpel; D Williams; J T Scott; N W Ramsey; F E Bruckner; C B Fearn
Journal: Ann Rheum Dis Date: 1973-03 Impact factor: 19.103

5. Biological hazards of radiation.

Authors: G W Dolphin
Journal: Ann Rheum Dis Date: 1973-12 Impact factor: 19.103

6. Leukocyte labeling with 51 chromium. 3. The kinetics of normal lymphocytes.

Authors: J L Scott; J G Davidson; J V Marino; R McMillan
Journal: Blood Date: 1972-08 Impact factor: 22.113

7. The tempo of lymphocyte recirculation from blood to lymph in the rat.

Authors: W L Ford; S J Simmonds
Journal: Cell Tissue Kinet Date: 1972-03

8. Indium-LLL labeled platelets: studies on preparation and evaluation of in vitro and in vivo functions.

Authors: M L Thakur; M J Welch; J H Joist; R E Coleman
Journal: Thromb Res Date: 1976-10 Impact factor: 3.944

Review 9. Lymphocyte migration and immune responses.

Authors: W L Ford
Journal: Prog Allergy Date: 1975

10. Indium-111-labeled leukocytes for the localization of abscesses: preparation, analysis, tissue distribution, and comparison with gallium-67 citrate in dogs.

Authors: M L Thakur; R E Coleman; M J Welch
Journal: J Lab Clin Med Date: 1977-01

12 in total

1. Fluorescent Dye Labeling of Erythrocytes and Leukocytes for Studying the Flow Dynamics in Mouse Retinal Circulation.

Authors: Rupesh Agrawal; Praveen Kumar Balne; Sai Bo Bo Tun; Yeo Sia Wey; Neha Khandelwal; Veluchamy A Barathi
Journal: J Vis Exp Date: 2017-07-03 Impact factor: 1.355

2. Significance of alteration in biodistribution of labeled lymphocytes exposed to stannous ion.

Authors: J L Tatum; J I Hirsch; T S Burke; M J Fratkin
Journal: Eur J Nucl Med Date: 1989

3. In vivo imaging of rat lymphocytes with an indium 111-labelled anti-T cell monoclonal antibody: a comparison with indium 111-labelled lymphocytes.

Authors: I Loutfi; P M Chisholm; D Bevan; J P Lavender
Journal: Eur J Nucl Med Date: 1990

An experimental comparison of radioactive labels with potential application to lymphocyte migration studies in patients.

1. [Drainage of the thoracic duct before transplantation in patients with chronic renal insufficiency].

2. A lymph node weight assay for the graft-versus-host activity of rat lymphoid cells.

3. Use of 99mTc as a radioisotopic label to study the migratory patterns of normal and neoplastic cells.

4. Cytogenetic and scanning study of patients receiving intra-articular injections of gold-198 and yttrium-90.

5. Biological hazards of radiation.

6. Leukocyte labeling with 51 chromium. 3. The kinetics of normal lymphocytes.

7. The tempo of lymphocyte recirculation from blood to lymph in the rat.

8. Indium-LLL labeled platelets: studies on preparation and evaluation of in vitro and in vivo functions.

Review 9. Lymphocyte migration and immune responses.

10. Indium-111-labeled leukocytes for the localization of abscesses: preparation, analysis, tissue distribution, and comparison with gallium-67 citrate in dogs.

1. Fluorescent Dye Labeling of Erythrocytes and Leukocytes for Studying the Flow Dynamics in Mouse Retinal Circulation.

2. Significance of alteration in biodistribution of labeled lymphocytes exposed to stannous ion.

3. In vivo imaging of rat lymphocytes with an indium 111-labelled anti-T cell monoclonal antibody: a comparison with indium 111-labelled lymphocytes.

4. A method for following human lymphocyte traffic using indium-111 oxine labelling.

5. Imaging pattern of radiolabelled lymphokine-activated killer cells in patients with metastatic malignant melanoma.

6. In vivo and in vitro effects of dexamethasone on leukocyte migration in the rat adjuvant arthritis model.

7. Lymphocyte labelling with indium: cytotoxicity studies.

8. Clinical usefulness of 111In-oxine-labeled autologous lymphocytes in kidney-graft rejection.

9. Measurement of lymphocyte traffic with indium-111.

10. Targeting of lipid vesicles: specificity of carbohydrate receptor analogues for leukocytes in mice.