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Literature DB >> 5894452

The effect of actidione on mitosis in the slime mold Physarum polycephalum.

Abstract

Actidione, reportedly a specific inhibitor of protein synthesis, was found to reduce the incorporation of labeled amino acids into proteins of the slime mold Physarum polycephalum without drastically inhibiting the incorporation of nucleic acid precursors into RNA. This inhibitor was found to completely block the ensuing mitosis if it was added at any time between telophase and late prophase. Plasmodia given Actidione in late prophase (about the time of nucleolar dissolution) went on through telophase to reconstruction even though nuclear amino acid incorporation was drastically reduced during that period.

Entities: Chemical Species

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Year: 1965 PMID： 5894452 PMCID： PMC2106721 DOI： 10.1083/jcb.27.2.337

Source DB: PubMed Journal: J Cell Biol ISSN： 0021-9525 Impact factor: 10.539

12 in total

6. Uridine diphosphoglucose pyrophosphorylase activity and differentiation in the cellular slime mold Physarum polycephaluno.

Authors: G D Kuehn
Journal: J Bacteriol Date: 1974-12 Impact factor: 3.490

10. Studies on the maintenance of oral development in Tetrahymena pyriformis GL-C. II. The relationship of protein synthesis to cell division and oral organelle development.

Authors: J Frankel
Journal: J Cell Biol Date: 1967-09 Impact factor: 10.539

10 in total

The effect of actidione on mitosis in the slime mold Physarum polycephalum.

1. INHIBITION OF DNA SYNTHESIS IN MAMMALIAN CELLS BY ACTIDIONE.

2. TEMPLATES FOR THE FIRST PROTEINS OF EMBRYONIC DEVELOPMENT.

Review 3. THE INTRACELLULAR TRANSFER OF GENETIC INFORMATION.

4. THE EFFECT OF ACTINOMYCIN D ON THE TIMING OF MITOSIS IN PHYSARUM POLYCEPHALUM.

5. Radiation sensitivity and the mitotic cycle in Vicia faba.

6. Morphological observations on growth and differentation of Physarum polycephalum grown in pure culture.

7. Division of a nucleus lacking a nucleolus.

8. Determination of serum proteins by means of the biuret reaction.

9. Protein measurement with the Folin phenol reagent.

10. The intracellular distribution and heterogeneity of ribonucleic acid in starfish oocytes.

Review 1. [Modern research on the cell cycle and mitosis in the myxomycete Physarum polycephalum].

2. Translational regulation of polysome formation during dormancy of Physarum polycephalum.

3. Activity of uridine diphosphate N-acetylglucosamine-4-epimerase during spherulation of Physarum polycephalum.

4. Activity of some enzymes in Physarum polycephalum. I. In the growing plasmodium.

5. Anion-Sensitive Mg ATP-Dependent Proton Pumping in Microsomal Membranes from Phycomyces blakesleeanus Bgff.

6. Uridine diphosphoglucose pyrophosphorylase activity and differentiation in the cellular slime mold Physarum polycephaluno.

7. Limited DNA synthesis in the absence of protein synthesis in Physarum polycephalum.

8. Effect of cycloheximide on the cell cycle of the crypts of the small intestine of the rat.

9. Synchronization of mitosis by the fusion of the plasmodia of Physarum polycephalum.

10. Studies on the maintenance of oral development in Tetrahymena pyriformis GL-C. II. The relationship of protein synthesis to cell division and oral organelle development.