Literature DB >> 5890452

Actinomycin D: inhibition of protein synthesis unrelated to effect on template RNA synthesis.

G R Honig, M Rabinovitz.   

Abstract

Incubation of sarcoma-37 ascites cells in vitro with actinomycin D resulted in inhibition of synthesis of nuclear and cytoplasmic proteins. The overall inhibition could be prevented or relieved by glucose; it is thus unrelated to breakdown of template RNA.

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Year:  1965        PMID: 5890452     DOI: 10.1126/science.149.3691.1504

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  24 in total

1.  Diphtheria toxin prevents catecholamine desensitization of A431 human epidermoid carcinoma cells.

Authors:  M DeBernardi; G Brooker
Journal:  Proc Natl Acad Sci U S A       Date:  1987-04       Impact factor: 11.205

2.  Comparative studies of the regeneration of HeLa cell receptors for poliovirus T1 and coxsackievirus B3.

Authors:  N H Levitt; R L Crowell
Journal:  J Virol       Date:  1967-08       Impact factor: 5.103

3.  Studies on the teratogenic phase specificity of actinomycin D in the rat.

Authors:  E Köhler; H J Merker
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1972       Impact factor: 3.000

4.  Studies on Phytoalexins: The Relationship between Actinomycin D and Ribonucleic Acid Synthesis during the Induction of Phaseollin in the French Bean (Phaseolus vulgaris L.).

Authors:  D R Biggs
Journal:  Plant Physiol       Date:  1972-12       Impact factor: 8.340

5.  Effects of inhibitors of RNA and protein synthesis on aspartate transcarbamylase activity in etiolated plant tissue.

Authors:  L B Johnson; C L Niblett; R F Lee
Journal:  Plant Physiol       Date:  1976-08       Impact factor: 8.340

6.  An early response to gibberellic Acid not requiring protein synthesis.

Authors:  Y Ben-Tal
Journal:  Plant Physiol       Date:  1974-12       Impact factor: 8.340

7.  The metabolism of soluble nucleotides in wheat aleurone layers treated with gibberellic Acid.

Authors:  G G Collins; C F Jenner; L G Paleg
Journal:  Plant Physiol       Date:  1972-03       Impact factor: 8.340

8.  Inhibition by actinomycin D of uridine diphosphoglucose synthetase activity during differentiation of Dictyostelium discoideum.

Authors:  B Wright; R Pannbacker
Journal:  J Bacteriol       Date:  1967-06       Impact factor: 3.490

9.  Differential inhibitory effects of actinomycin D among strains of poliovirus.

Authors:  F L Schaffer; M Gordon
Journal:  J Bacteriol       Date:  1966-06       Impact factor: 3.490

10.  Effect of bacterial endotoxin and inhibitors on tryptophan oxygenase induction in mouse liver slices.

Authors:  J M Greene; L J Berry
Journal:  J Bacteriol       Date:  1968-12       Impact factor: 3.490

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