Literature DB >> 588466

Topical mechlorethamine therapy for mycosis fungoides.

N M Price, V S Constantine, R T Hoppe, Z Y Fuks, E M Farber.   

Abstract

Patients with limited skin involvement by mycosis fungoides were treated with daily topical mechlorethamine. Seven of thirteen patients had a complete remission of diseases. Six of these seven experienced a contact dermatitis and four underwent a successful topical desensitization programme. The possible beneficial therapeutic effects of developing a contact allergy are discussed.

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Year:  1977        PMID: 588466     DOI: 10.1111/j.1365-2133.1977.tb14133.x

Source DB:  PubMed          Journal:  Br J Dermatol        ISSN: 0007-0963            Impact factor:   9.302


  2 in total

Review 1.  Clinical potential of mechlorethamine gel for the topical treatment of mycosis fungoides-type cutaneous T-cell lymphoma: a review on current efficacy and safety data.

Authors:  Kendall Liner; Celeste Brown; Laura Y McGirt
Journal:  Drug Des Devel Ther       Date:  2018-01-31       Impact factor: 4.162

2.  Randomized Mechlorethamine/Chlormethine Induced Dermatitis Assessment Study (MIDAS) Establishes Benefit of Topical Triamcinolone 0.1% Ointment Cotreatment in Mycosis Fungoides.

Authors:  Carolina V Alexander-Savino; Catherine G Chung; Elaine S Gilmore; Sean M Carroll; Brian Poligone
Journal:  Dermatol Ther (Heidelb)       Date:  2022-02-05
  2 in total

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