Literature DB >> 588439

The effect of irradiation on demyelination induced by avirulent Semliki Forest virus.

M Chew-Lim, H E Webb, S Jagelman.   

Abstract

A dose of 500 rad total body irradiation before Semliki Forest virus infection was the most effective in producing multiple foci of demyelination in Swiss mice. Animals receiving this dose had the highest virus titre of Semliki Forest virus persisting in the brain and a delayed antibody response. In spite of extensive demyelination no obvious clinical signs such as paralysis were observed.

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Mesh：

Year:  1977        PMID： 588439      PMCID： PMC2041266     

Source DB:  PubMed          Journal:  Br J Exp Pathol        ISSN： 0007-1021


  8 in total

1.  Studies on the nature of the nature of the neutralization reaction and the competition for neutralizing antibody between components of the virus system of foot-and-mouth disease.

Authors:  C J BRADISH; J O FARLEY; H E FERRIER
Journal:  Virology       Date:  1962-11       Impact factor: 3.616

2.  A method for the combined staining of cells and fibers in the nervous system.

Authors:  H KLUVER; E BARRERA
Journal:  J Neuropathol Exp Neurol       Date:  1953-10       Impact factor: 3.685

3.  Response of irradiated mice to live-virus (TC-83) immunization.

Authors:  R O Spertzel; D E Hilmas; J R Brown; D W Mason
Journal:  Infect Immun       Date:  1975-03       Impact factor: 3.441

4.  Maintenance of latent herpetic infection: an apparent role for anti-viral IgG.

Authors:  J G Stevens; M L Cook
Journal:  J Immunol       Date:  1974-12       Impact factor: 5.422

5.  Langat virus encephalitis in mice. II. The effect of irradiation.

Authors:  H E Webb; D G Wight; G Wiernik; G S Platt; C E Smith
Journal:  J Hyg (Lond)       Date:  1968-09

6.  The virulence of original and derived strains of Semliki forest virus for mice, guinea-pigs and rabbits.

Authors:  C J Bradish; K Allner; H B Maber
Journal:  J Gen Virol       Date:  1971-08       Impact factor: 3.891

Review 7.  Immunosuppression: a means to assess the role of the immune response in acute virus infections.

Authors:  N Nathanson; G A Cole
Journal:  Fed Proc       Date:  1971 Nov-Dec

8.  Brain lysosomal glycosidase activity in immunosuppressed mice infected with avirulent Semliki forest virus.

Authors:  A J Suckling; S Jagelman; H E Webb
Journal:  Infect Immun       Date:  1977-02       Impact factor: 3.441
  8 in total
  5 in total

1.  Semliki Forest virus induced, immune mediated demyelination: the effect of irradiation.

Authors:  J K Fazakerley; H E Webb
Journal:  Br J Exp Pathol       Date:  1987-02

2.  Demyelination in mice resulting from infection with a mutant of Semliki Forest virus.

Authors:  B J Sheahan; P N Barrett; G J Atkins
Journal:  Acta Neuropathol       Date:  1981       Impact factor: 17.088

3.  Brain viral persistence and myelin damage in nude mice.

Authors:  M Chew-Lim
Journal:  Can J Comp Med       Date:  1979-01

4.  CNS pathogenesis following a dual viral infection with Semliki Forest (alphavirus) and Langat (flavivirus).

Authors:  S Amor; H E Webb
Journal:  Br J Exp Pathol       Date:  1988-04

5.  Reconstitution of Semliki forest virus infected mice, induces immune mediated pathological changes in the CNS.

Authors:  J K Fazakerley; S Amor; H E Webb
Journal:  Clin Exp Immunol       Date:  1983-04       Impact factor: 4.330
  5 in total

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