Literature DB >> 588313

Accumulation of methotrexate diglutamate in human liver during methotrexate therapy.

S A Jacobs, C J Derr, D G Johns.   

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Year:  1977        PMID： 588313     DOI： 10.1016/0006-2952(77)90296-9

Source DB:  PubMed          Journal:  Biochem Pharmacol        ISSN： 0006-2952            Impact factor:   5.858


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  9 in total

Review 1.  Polyglutamation of methotrexate. Is methotrexate a prodrug?

Authors:  B A Chabner; C J Allegra; G A Curt; N J Clendeninn; J Baram; S Koizumi; J C Drake; J Jolivet
Journal:  J Clin Invest       Date:  1985-09       Impact factor: 14.808

2.  Formation of methotrexate polyglutamates in purified myeloid precursor cells from normal human bone marrow.

Authors:  S Koizumi; G A Curt; R L Fine; J D Griffin; B A Chabner
Journal:  J Clin Invest       Date:  1985-03       Impact factor: 14.808

3.  5-fluorouracil-methotrexate synergy: enhancement of 5-fluorodeoxyridylate binding to thymidylate synthase by dihydropteroylpolyglutamates.

Authors:  D J Fernandes; J R Bertino
Journal:  Proc Natl Acad Sci U S A       Date:  1980-10       Impact factor: 11.205

4.  Insulin effects on methotrexate polyglutamate synthesis and enzyme binding in cultured human breast cancer cells.

Authors:  R L Schilsky; F S Ordway
Journal:  Cancer Chemother Pharmacol       Date:  1985       Impact factor: 3.333

5.  Synthesis, retention, and biological activity of methotrexate polyglutamates in cultured human breast cancer cells.

Authors:  J Jolivet; R L Schilsky; B D Bailey; J C Drake; B A Chabner
Journal:  J Clin Invest       Date:  1982-08       Impact factor: 14.808

Review 6.  Clinical pharmacokinetics of commonly used anticancer drugs.

Authors:  F M Balis; J S Holcenberg; W A Bleyer
Journal:  Clin Pharmacokinet       Date:  1983 May-Jun       Impact factor: 6.447

Review 7.  Pteroylpolyglutamates.

Authors:  R L Kisliuk
Journal:  Mol Cell Biochem       Date:  1981-09-25       Impact factor: 3.396

8.  Impairment of methotrexate (MTX)-polyglutamate formation of MTX-resistant K562 cell lines.

Authors:  S Koizumi
Journal:  Jpn J Cancer Res       Date:  1988-11

9.  Reversal of methotrexate cytotoxicity to human bone marrow cells and leukemic K562 cells by leucovorin: methotrexate polyglutamates formation as a possible important factor.

Authors:  S Koizumi; Y Ueno; I Ohno; T Ichihara; Y Tamaru; H Matsukawa
Journal:  Jpn J Cancer Res       Date:  1990-11
  9 in total

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