Literature DB >> 5866660

Steroid stimulation of beating of cultured rat-heart cells.

R L McCarl, B F Szuhaj, R T Houlihan.   

Abstract

The addition of cortisol acetate and deoxycorticosterone acetate to cultured heart cells from rats, 4 to 6 days old, stimulated and prolonged beating. Protein synthesis was slowed down in the presence of steroids. Addition of steroids to cells that had stopped beating caused the reestablishiment of the beat.

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Year:  1965        PMID： 5866660     DOI： 10.1126/science.150.3703.1611

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  5 in total

1.  Cell models in the study of mechanisms of toxicity.

Authors:  J R Walton; I K Buckley
Journal:  Agents Actions       Date:  1975-02

2.  Rate of uptake of endogenous cortisol by the left ventricle of the anaesthetized dog during ventilation with ambient air and during hypoxia.

Authors:  J Kolanowski; J Lammerant
Journal:  J Physiol       Date:  1973-09       Impact factor: 5.182

3.  Effects of cortisol on cultured rat heart cells: lipase activity, fatty acid oxidation, glycogen metabolism, and ATP levels as related to the beating phenomenon.

Authors:  J V Anastasia; R L McCarl
Journal:  J Cell Biol       Date:  1973-04       Impact factor: 10.539

4.  The effects of actinomycin D on protein synthesis and beating in cultured rat heart cells.

Authors:  R L McCarl; R C Shaler
Journal:  J Cell Biol       Date:  1969-03       Impact factor: 10.539

5.  The mechanism of cortisol action in cultured rat heart cells. Effects on RNA and protein synthesis.

Authors:  R C Shaler; R L McCarl
Journal:  J Cell Biol       Date:  1971-04       Impact factor: 10.539
  5 in total

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