| Literature DB >> 5862499 |
Abstract
A high molecular weight fraction of a soluble Marsh muscle-relaxing preparation has been shown to contain a calcium-complexing substance. By examining the nature of the competition between this fraction and chelex-100 for calcium at various total calcium concentrations it has been possible to calculate the concentration and calcium stability constant of this calcium-complexing substance. Taking into account dilutions which occur during the preparation of fractions containing this substance its concentration may be estimated at about 2.10(-4) in muscle and its calcium stability constant was found to be about 1.5.10(5)M(-1). Preliminary evidence suggests that the calcium-binding substance is a protein.Entities:
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Year: 1965 PMID: 5862499 PMCID: PMC2195472
Source DB: PubMed Journal: J Gen Physiol ISSN: 0022-1295 Impact factor: 4.086