Literature DB >> 583641

The adjuvant effect of tuberculin in experimental sensitization to merthiolate.

B Magnusson, H Möller.   

Abstract

When guinea pigs were sensitized to tuberculin by exposure to complete Freund's adjuvant the size of the intradermal PPD test was positively correlated to the body weight of the animal. Old Tuberculin showed stimulating effect in a subsequent sensitization to merthiolate (thimerosal). The high frequency of delayed cutaneous allergy to merthiolate in Swedish population is probably explained by sensitization through intradermal testing with tuberculin containing merthiolate as a preservative.

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Year:  1977        PMID： 583641     DOI： 10.1007/bf00561125

Source DB:  PubMed          Journal:  Arch Dermatol Res            Impact factor:   3.017


  8 in total

1.  Delayed cutaneous reactions in the rat.

Authors:  M H FLAX; B H WAKSMAN
Journal:  J Immunol       Date:  1962-10       Impact factor: 5.422

2.  The measurement of tuberculin hypersensitivity in rats.

Authors:  M J Lefford
Journal:  Int Arch Allergy Appl Immunol       Date:  1974

3.  Intracutaneous test reactions to tuberculin containing merthiolate as a preservative.

Authors:  H Hansson; H Möller
Journal:  Scand J Infect Dis       Date:  1971

4.  Patch test reactions to merthiolate in healthy young subjects.

Authors:  H Hansson; H Möller
Journal:  Br J Dermatol       Date:  1970-09       Impact factor: 9.302

5.  The identification of contact allergens by animal assay. The guinea pig maximization test.

Authors:  B Magnusson; A M Kligman
Journal:  J Invest Dermatol       Date:  1969-03       Impact factor: 8.551

6.  The identification of contact allergens by human assay. II. Factors influencing the induction and measurement of allergic contact dermatitis.

Authors:  A M Kligman
Journal:  J Invest Dermatol       Date:  1966-11       Impact factor: 8.551

7.  Merthiolate testing in twins.

Authors:  R Holst; H Möller
Journal:  Contact Dermatitis       Date:  1975-12       Impact factor: 6.600

8.  The adjuvant activity of mycobacterial RNA preparations and synthetic polynucleotides for induction of delayed hypersensitivity to purified protein derivative in guinea pigs.

Authors:  C H Casavant; G P Youmans
Journal:  J Immunol       Date:  1975-03       Impact factor: 5.422
  8 in total

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