Literature DB >> 5835873

Demethylation of trimethadione and metharbital by rat liver microsomal enzymes: substrate concentration--yield relationships and competition between substrates.

T C Butler, W J Waddell, D T Poole.   

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Year:  1965        PMID： 5835873     DOI： 10.1016/0006-2952(65)90245-5

Source DB:  PubMed          Journal:  Biochem Pharmacol        ISSN： 0006-2952            Impact factor:   5.858


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  4 in total

1.  Anticonvulsant drugs. I. Patho-physiological and pharmacological aspects.

Authors:  H Kutt; S Louis
Journal:  Drugs       Date:  1972       Impact factor: 9.546

2.  Clinical significance of the trimethadione tolerance test in chronic hepatitis: a useful indicator of hepatic drug metabolizing capacity.

Authors:  M Abei; E Tanaka; N Tanaka; Y Matsuzaki; T Ikegami; A Ishikawa; T Osuga
Journal:  J Gastroenterol       Date:  1995-08       Impact factor: 7.527

3.  The physiological disposition of 14 C-methsuximide in the rat.

Authors:  P J Nicholls; T C Orton
Journal:  Br J Pharmacol       Date:  1972-05       Impact factor: 8.739

4.  Effects of the oxazolidinedione anticonvulsants trimethadione and dimethadione and the barbiturate homolog 5,5-dimethylbarbituric acid on N-nitrosodiethylamine-initiated renal and hepatic carcinogenesis in the F344/NCr rat.

Authors:  B A Diwan; R W Nims; J R Henneman; J M Ward; R A Lubet; J M Rice
Journal:  Arch Toxicol       Date:  1992       Impact factor: 5.153
  4 in total

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