Literature DB >> 582776

Sugar-oximes, new potential antidotes against organophosphorus poisoning.

E S Rachaman, Y Ashani, H Leader, I Granoth, H Edery, G Porath.   

Abstract

In attempt to improve distribution and transport qualities of antidotes against organophosphorus poisoning, a new series of pyridine aldoximes linked to glucose moiety were synthesized and studied both in vivo and in vitro. Preliminary results describing the biological activity of the new compounds are presented and discussed in this report.

Entities:  

Mesh:

Substances:

Year:  1979        PMID: 582776     DOI: 10.1002/chin.197938312

Source DB:  PubMed          Journal:  Arzneimittelforschung        ISSN: 0004-4172


  2 in total

Review 1.  Oxime-mediated reactivation of organophosphate-inhibited acetylcholinesterase with emphasis on centrally-active oximes.

Authors:  Janice E Chambers; Mary B Dail; Edward C Meek
Journal:  Neuropharmacology       Date:  2020-06-13       Impact factor: 5.250

Review 2.  Central neuroprotection demonstrated by novel oxime countermeasures to nerve agent surrogates.

Authors:  Janice E Chambers; Edward C Meek
Journal:  Ann N Y Acad Sci       Date:  2020-04-21       Impact factor: 6.499

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.