| Literature DB >> 5827724 |
A B Robinson, K F Manly, M P Anthony, J F Catchpool, L Pauling.
Abstract
Potency of anesthetics is quantitatively measured with laboratory-hatched larvae of the brine shrimp Artemia salina. Statistical fluctuations are minimized in that 100,000 animals are used to determine a single median anesthetic dose value. The technique was developed to study molecular mechanisms of general anesthesia.Entities:
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Year: 1965 PMID: 5827724 DOI: 10.1126/science.149.3689.1255
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728