Literature DB >> 582750

A new easily accessible steric parameter for structure-activity relationships.

V Austel, E Kutter, W Kalbfleisch.   

Abstract

A simple steric parameter Sb is formulated on the basis of substituent branching. This parameter can be calculated for every conceivable substituent and gives an estimate of steric effects which is sufficient for most purposes in practical drug design. Sb may also be applied to quantitative structure-activity relationships.

Entities:  

Mesh:

Year:  1979        PMID: 582750

Source DB:  PubMed          Journal:  Arzneimittelforschung        ISSN: 0004-4172


  1 in total

1.  Pattern recognition study of QSAR substituent descriptors.

Authors:  H van de Waterbeemd; N el Tayar; P A Carrupt; B Testa
Journal:  J Comput Aided Mol Des       Date:  1989-06       Impact factor: 3.686

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.