| Literature DB >> 582750 |
V Austel, E Kutter, W Kalbfleisch.
Abstract
A simple steric parameter Sb is formulated on the basis of substituent branching. This parameter can be calculated for every conceivable substituent and gives an estimate of steric effects which is sufficient for most purposes in practical drug design. Sb may also be applied to quantitative structure-activity relationships.Entities:
Mesh:
Year: 1979 PMID: 582750
Source DB: PubMed Journal: Arzneimittelforschung ISSN: 0004-4172