Literature DB >> 5826525

Induction in vitro of antibodies to phage T2: antigens in the RNA extract employed.

H P Friedman, A B Stavitsky, J M Solomon.   

Abstract

Cells from rat peritoneal exudate incubated in vitro with phage T2 yield RNA which induces cultures of rat lymph nodes to form antibodies. Complement fixation reveals T2 head, tail, and internal protein antigens in the RNA. Inoculating the RNA into mice that had previously been stimulated primarily with whole phage T2 results in a secondary response of neutralizing antibody.

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Year:  1965        PMID: 5826525     DOI: 10.1126/science.149.3688.1106

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  33 in total

1.  Effect of immunization on the RNA polymerase activity of guinea-pig macrophage nuclei.

Authors:  M Went; N Simon
Journal:  Arch Dermatol Res       Date:  1976-06-21       Impact factor: 3.017

Review 2.  Gene activation during immune reaction.

Authors:  D Jachertz
Journal:  Mol Cell Biochem       Date:  1979-03-19       Impact factor: 3.396

3.  Transfer of antigenic macromolecules from macrophages to lymphocytes. I. Autoradiographic and quantitative study of ( 14 C)endotoxin and ( 125 I)haemocyanin transfer.

Authors:  C Bona; A Anteunis; R Robineaux; A Astesano
Journal:  Immunology       Date:  1972-12       Impact factor: 7.397

4.  [Synthesis of antibodies in vitro. 8. On the action of the messenger-RNA molecule on spleen cell culture].

Authors:  D Jacherts
Journal:  Z Med Mikrobiol Immunol       Date:  1968

Review 5.  The gamma system, pathology and therapeutics.

Authors:  R H De Lellis
Journal:  Postgrad Med J       Date:  1969-02       Impact factor: 2.401

6.  Nucleases in immunity. II. Ineffectiveness of exogenous RNase on the antibody plaque response of immunized mice.

Authors:  A K Chakrabarty; H Friedman
Journal:  Clin Exp Immunol       Date:  1970-04       Impact factor: 4.330

Review 7.  [Immunologic function of monocytes and macrophages].

Authors:  H Huber; H H Fudenberg
Journal:  Klin Wochenschr       Date:  1969-10-15

8.  Affinity of antigen for white cells and its relation to the induction of antibody formation.

Authors:  D Sulitzeanu
Journal:  Bacteriol Rev       Date:  1968-12

9.  [Antibody synthesis in vitro. V. The transmission of information from the antigen-producing cell to the antibody-producing cell].

Authors:  D Jacherts; H Noltenius
Journal:  Z Med Mikrobiol Immunol       Date:  1966-04-25

Review 10.  Transfer of tumor specific immunity with "immune" RNA: prospects for the treatment of human cancer.

Authors:  D Fritze; D H Kern; Y H Pilch
Journal:  Klin Wochenschr       Date:  1976-09-15
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