Literature DB >> 5821218

Cardiac sympathetic nerve activity: changes induced by ouabain and propranolol.

R A Gillis.   

Abstract

A study of the effects of ouabain and propranolol on the spontaneous activity in the preganglionic sympathetic nerves to the cat heart showed that ouabain can produce both an inhibition and a stimulation of the spontaneous activity in sympathetic nerves. The inhibition appears to be reflex in nature and is not present when the buffer nerves are sectioned. The stimulation is correlated with the development of cardiac arrhythmias and is antagonized by propranolol.

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Year:  1969        PMID: 5821218     DOI: 10.1126/science.166.3904.508

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  7 in total

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Journal:  Indian J Pediatr       Date:  1988 Jan-Feb       Impact factor: 1.967

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Journal:  Klin Wochenschr       Date:  1983-05-16

3.  Evidence for participation of catecholamines in cardiac action of ouabain: positive chronotropic effect.

Authors:  E Seifen
Journal:  Br J Pharmacol       Date:  1974-08       Impact factor: 8.739

4.  Accumulation of radioactive cardiac glycosides by various brain regions in relation to the dysrhythmogenic effect.

Authors:  S Dutta; B H Marks; E P Schoener
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5.  Origin of acetyl strophanthidin-induced ventricular arrhythmias.

Authors:  P O Ettinger; J Calabro; T J Regan; H A Oldewurtel
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6.  Effects of microinjection of ouabain into the hypothalamus in cats.

Authors:  B N Basu Ray; W M Booker; S N Dutta; S N Pradhan
Journal:  Br J Pharmacol       Date:  1972-06       Impact factor: 8.739

7.  The central nervous system as a site of action for the coronary vasoconstrictor effect of digoxin.

Authors:  H Garan; T W Smith; W J Powell
Journal:  J Clin Invest       Date:  1974-12       Impact factor: 14.808

  7 in total

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