Literature DB >> 5818039

Sweat in schizophrenic patients: identification of the odorous substance.

K Smith, G F Thompson, H D Koster.   

Abstract

The substance causing the peculiar odor in sweat of schizophrenic patients has been isolated and identified as trans-3-methyl-2-hexenoic acid by gas chromatography, mass spectrometry, and nuclear magnetic resonance spectroscopy. The natural and the synthetic compounds were cleaves across the double bond to give 2-pentanone and oxalic acid, thereby confirming the structure.

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Year:  1969        PMID： 5818039     DOI： 10.1126/science.166.3903.398

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  10 in total

Review 1.  Advances in electronic-nose technologies developed for biomedical applications.

Authors:  Alphus D Wilson; Manuela Baietto
Journal:  Sensors (Basel)       Date:  2011-01-19       Impact factor: 3.576

2.  Smell as a diagnostic marker.

Authors:  K Liddell
Journal:  Postgrad Med J       Date:  1976-03       Impact factor: 2.401

3.  Responses of Human Neonates to Highly Diluted Odorants from Sweat.

Authors:  Helene M Loos; Sébastien Doucet; Fanny Védrines; Constanze Sharapa; Robert Soussignan; Karine Durand; Paul Sagot; Andrea Buettner; Benoist Schaal
Journal:  J Chem Ecol       Date:  2017-01-06       Impact factor: 2.626

4.  The behavioural role of the mammalian skin glands.

Authors:  R Mykytowycz
Journal:  Naturwissenschaften       Date:  1972-04

5.  Schizophrenia: evidence for the major gene hypothesis.

Authors:  R C Elston; M A Campbell
Journal:  Behav Genet       Date:  1970-02       Impact factor: 2.805

6.  Analysis of characteristic odors from human male axillae.

Authors:  X N Zeng; J J Leyden; H J Lawley; K Sawano; I Nohara; G Preti
Journal:  J Chem Ecol       Date:  1991-07       Impact factor: 2.626

7.  [Determination and occurrence of 3,4-dimethoxyphenylethylamine (DMPEA) in the urine of acute schizophrenics (author's transl)].

Authors:  G Braun; D A Kalbhen; J Müller; H Vahar-Matiar
Journal:  Arch Psychiatr Nervenkr (1970)       Date:  1974-03-04

Review 8.  [Evaluating function and disorders of smell].

Authors:  C Herberhold
Journal:  Arch Otorhinolaryngol       Date:  1975

9.  The bedside Sherlock Holmes.

Authors:  F T Fitzgerald; L M Tierney
Journal:  West J Med       Date:  1982-08

Review 10.  Advances in electronic-nose technologies for the detection of volatile biomarker metabolites in the human breath.

Authors:  Alphus D Wilson
Journal:  Metabolites       Date:  2015-03-02
  10 in total

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