Literature DB >> 5815255

Transplantation of pluripotential nuclei from triploid frog tumors.

R G McKinnell, B A Deggins, D D Labat.   

Abstract

Renal tumors were produced by injection of a cell fraction of a tumor into triploid tadpoles of Rana pipiens before they began feeding. Triploid tumor cells were dissociated and transplanted into activated and enucleated eggs. Pluripotency of the implanted nuclei was evidenced by the formation of swimming triploid tadpoles.

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Year:  1969        PMID: 5815255     DOI: 10.1126/science.165.3891.394

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  31 in total

1.  Allografts of tumor nuclear transplantation embryos: differentiation competence.

Authors:  J M Lust; D L Carlson; R Kowles; L Rollins-Smith; J W Williams; R G McKinnell
Journal:  Proc Natl Acad Sci U S A       Date:  1991-08-01       Impact factor: 11.205

Review 2.  Nuclear transfer to eggs and oocytes.

Authors:  J B Gurdon; Ian Wilmut
Journal:  Cold Spring Harb Perspect Biol       Date:  2011-06-01       Impact factor: 10.005

Review 3.  Constructing and Deconstructing Cancers using Human Pluripotent Stem Cells and Organoids.

Authors:  Ryan C Smith; Viviane Tabar
Journal:  Cell Stem Cell       Date:  2018-12-20       Impact factor: 24.633

Review 4.  Some studies on early embryonic development relevant to the study of cancer.

Authors:  H R Woodland
Journal:  J Clin Pathol Suppl (R Coll Pathol)       Date:  1974

5.  An epigenetic mechanism for carcinogenesis.

Authors:  R Tsanev; B Sendov
Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol       Date:  1971

6.  Cytoplasmic mediation of malignancy.

Authors:  B A Israel; W I Schaeffer
Journal:  In Vitro Cell Dev Biol       Date:  1988-05

Review 7.  Control of cancer formation by intrinsic genetic noise and microenvironmental cues.

Authors:  Amy Brock; Silva Krause; Donald E Ingber
Journal:  Nat Rev Cancer       Date:  2015-07-09       Impact factor: 60.716

8.  Cancer as a metabolic disease.

Authors:  Thomas N Seyfried; Laura M Shelton
Journal:  Nutr Metab (Lond)       Date:  2010-01-27       Impact factor: 4.169

9.  Cytoplasmic suppression of malignancy.

Authors:  B A Israel; W I Schaeffer
Journal:  In Vitro Cell Dev Biol       Date:  1987-09

10.  Cytotoxicity of unsaturated fatty acids in fresh human tumor explants: concentration thresholds and implications for clinical efficacy.

Authors:  David E Scheim
Journal:  Lipids Health Dis       Date:  2009-12-15       Impact factor: 3.876

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