Literature DB >> 5812636

Studies on the purification of antihemophilic factor (factor 8. I. Precipitation of antihemophilic factor by concanavalin A.

L Kass, O D Ratnoff, M A Leon.   

Abstract

Concanavalin A precipitates antihemophilic factor from normal plasma. Combining this precipitation with other techniques, we were able to separate fractions rich in antihemophilic activity from human plasma with rapidity. The molecular weight of antihemophilic factor was estimated to be greater than 2 million. Presumably, antihemophilic factor is a large glycoprotein.

Entities:  

Mesh：

Substances：

Year:  1969        PMID： 5812636      PMCID： PMC322226          DOI： 10.1172/JCI105991

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


  24 in total

1.  HIGH-POTENCY ANTIHAEMOPHILIC FACTOR CONCENTRATE PREPARED FROM CRYOGLOBULIN PRECIPITATE.

Authors:  J G POOL; E J GERSHGOLD; A R PAPPENHAGEN
Journal:  Nature       Date:  1964-07-18       Impact factor: 49.962

2.  SIMPLIFIED "DISC" (POLYACRYLAMIDE GEL) ELECTROPHORESIS.

Authors:  J T CLARKE
Journal:  Ann N Y Acad Sci       Date:  1964-12-28       Impact factor: 5.691

3.  The purification of activated Hageman factor (activated factor XII).

Authors:  O D RATNOFF; E W DAVIE
Journal:  Biochemistry       Date:  1962-11       Impact factor: 3.162

4.  Specific protein of legumes which reacts with animal proteins.

Authors:  S NAKAMURA; K TANAKA; S MURAKAWA
Journal:  Nature       Date:  1960-10-08       Impact factor: 49.962

5.  An improved technique of agar-gel electrophoresis on microscope slides.

Authors:  R J WIEME
Journal:  Clin Chim Acta       Date:  1959-05       Impact factor: 3.786

6.  Observations on plasma banking and transfusion procedures for haemophilic patients using a quantitative assay for antihaemophilic globulin (AHG).

Authors:  J G POOL; J ROBINSON
Journal:  Br J Haematol       Date:  1959-01       Impact factor: 6.998

7.  A method for determining the sedimentation behavior of enzymes: application to protein mixtures.

Authors:  R G MARTIN; B N AMES
Journal:  J Biol Chem       Date:  1961-05       Impact factor: 5.157

8.  Protein-carbonhydrate interaction. 3. Agar gel-diffusion studies on the interaction of Concanavalin A, a lectin isolated from jack bean, with polysaccharides.

Authors:  I J Goldstein; L L So
Journal:  Arch Biochem Biophys       Date:  1965-08       Impact factor: 4.013

9.  Concanavalin A reaction with human normal immunoglobulin G and myeloma immunoglobulin G.

Authors:  M A Leon
Journal:  Science       Date:  1967-12-08       Impact factor: 47.728

10.  Observations on hemophilia, parahemophilia, and coexistent hemophilia and parahemophilia; alterations in the platelets and the thromboplastin generation test.

Authors:  R H SEIBERT; A MARGOLIUS; O D RATNOFF
Journal:  J Lab Clin Med       Date:  1958-09
View more
  12 in total

1.  Studies on human antihemophilic factor. Evidence for a covalently linked subunit structure.

Authors:  M E Switzer; P A McKee
Journal:  J Clin Invest       Date:  1976-04       Impact factor: 14.808

2.  Studies on a complex mechanism for the activation of plasminogen by kaolin and by chloroform: the participation of Hageman factor and additional cofactors.

Authors:  D Ogston; C M Ogston; O D Ratnoff; C D Forbes
Journal:  J Clin Invest       Date:  1969-10       Impact factor: 14.808

3.  Studies of the human factor VIII/von Willebrand factor protein. III. Qualitative defects in von Willebrand's disease.

Authors:  H R Gralnick; B S Coller; Y Sultan
Journal:  J Clin Invest       Date:  1975-10       Impact factor: 14.808

4.  Studies on the nature of antihemophilic factor (factor VIII). Further evidence relating the AHF-like antigens in normal and hemophilic plasmas.

Authors:  B Bennett; W B Forman; O D Ratnoff
Journal:  J Clin Invest       Date:  1973-09       Impact factor: 14.808

5.  The subunit structure of normal and hemophilic factor VIII.

Authors:  G A Shapiro; J C Andersen; S V Pizzo; P A McKee
Journal:  J Clin Invest       Date:  1973-09       Impact factor: 14.808

6.  Partial purification of plasma thromboplastin antecedent (factor XI) and its activation by trypsin.

Authors:  H Saito; O D Ratnoff; J S Marshall; J Pensky
Journal:  J Clin Invest       Date:  1973-04       Impact factor: 14.808

7.  Some effects of calcium on the activation of human factor VIII/Von Willebrand factor protein by thrombin.

Authors:  M E Switzer; P A McKee
Journal:  J Clin Invest       Date:  1977-10       Impact factor: 14.808

8.  Studies on the purification of antihemophilic factor (factor VIII). II. Separation of partially purified antihemophilic factor by gel filtration of plasma.

Authors:  O D Ratnoff; L Kass; P D Lang
Journal:  J Clin Invest       Date:  1969-05       Impact factor: 14.808

9.  Studies on the purification and characterization of human factor 8.

Authors:  S L Marchesi; N R Shulman; H R Gralnick
Journal:  J Clin Invest       Date:  1972-08       Impact factor: 14.808

10.  Defective ristocetin-induced platelet aggregation in von Willebrand's disease and its correction by factor VIII.

Authors:  H J Weiss; J Rogers; H Brand
Journal:  J Clin Invest       Date:  1973-11       Impact factor: 14.808
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.