Literature DB >> 581162

Effects of alpha- and beta-adrenergic receptor blockade on the isoamylases of rat-parotid gland.

R Chilla, C Arglebe.   

Abstract

The in vivo activity of rat-parotid isoamylases was increased following alpha-receptor block by phentolamine. Additional inhibition of the beta-receptors by propranolol did not further augment the isoenzyme activities. After 21 days, the isoamylase concentrations were even lower than after alpha-receptor block alone. Based upon these results, an alpha-receptor mediated discharge from the duct system of already secreted gland protein and a possible role of the alpha-receptors in protein secretion from the parotid gland are discussed.

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Year:  1978        PMID: 581162     DOI: 10.1007/bf00457486

Source DB:  PubMed          Journal:  Arch Otorhinolaryngol        ISSN: 0302-9530


  17 in total

1.  Dispersed rat parotid acinar cells. II. Characterization of adrenergic receptors.

Authors:  J A Mangos; N R McSherry; T Barber; S N Arvanitakis; V Wagner
Journal:  Am J Physiol       Date:  1975-09

2.  Dispersed rat parotid acinar cells. I. Morphological and functional characterization.

Authors:  J A Mangos; N R McSherry; F Butcher; K Irwin; T Barber
Journal:  Am J Physiol       Date:  1975-09

3.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

Review 4.  Degeneration activity after parasympathetic or sympathetic denervation.

Authors:  N Emmelin; U Trendelenburg
Journal:  Ergeb Physiol       Date:  1972

5.  Potassium release mediated by the epinephrine -receptor in rat parotid slices. Properties and relation to enzyme secretion.

Authors:  S Batzri; Z Selinger; M Schramm; M R Robinovitch
Journal:  J Biol Chem       Date:  1973-01-10       Impact factor: 5.157

6.  Potassium ion release and enzyme secretion: adrenergic regulation by alpha- and beta-receptors.

Authors:  S Batzri; Z Selinger; M Schramm
Journal:  Science       Date:  1971-12-03       Impact factor: 47.728

7.  Age-dependent changes in the alpha-isoamylase pattern of human and rat parotid glands.

Authors:  R Chilla; H Niemann; C Arglebe; G F Domagk
Journal:  ORL J Otorhinolaryngol Relat Spec       Date:  1974       Impact factor: 1.538

8.  On the nature of the molecular heterogeneity of rat parotid amylase.

Authors:  M R Robinovitch; L M Sreebny
Journal:  Arch Oral Biol       Date:  1972-03       Impact factor: 2.633

9.  The function of alpha- and beta-adrenergic receptors and a cholinergic receptor in the secretory cell of rat parotid gland.

Authors:  M Schramm; Z Selinger
Journal:  Adv Cytopharmacol       Date:  1974

10.  [Sialoadenosis produced by drug-treatment of hypertonicity. I. Experimental studies on the effects of guanethidine (Ismelin) on the parotid glands of the rat (author's transl)].

Authors:  R Chilla; R Rieger; C Arglebe
Journal:  Arch Otorhinolaryngol       Date:  1975-07-15
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