Literature DB >> 581030

n-Butoxyacetic acid, a urinary metabolite from inhaled n-butoxyethanol (Butylcellosolve).

A K Jönsson, G Steen.   

Abstract

Male albino rats were exposed to butylcellosolve (n-butoxyethanol). Collected urine was found to contain a characteristic metabolite, identified as n-butoxyacetic acid by mass spectrometry. The identity of the compound was confirmed by synthesis.

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Year:  1978        PMID： 581030     DOI： 10.1111/j.1600-0773.1978.tb02216.x

Source DB:  PubMed          Journal:  Acta Pharmacol Toxicol (Copenh)        ISSN： 0001-6683


  12 in total

1.  Analysis of ethylene glycol ether metabolites in urine by extractive alkylation and electron-capture gas chromatography.

Authors:  G Johanson
Journal:  Arch Toxicol       Date:  1989       Impact factor: 5.153

2.  Ethoxyacetic acid: a metabolite of ethylene glycol monoethyl ether acetate in man.

Authors:  D Groeseneken; H Veulemans; R Masschelein; E Van Vlem
Journal:  Br J Ind Med       Date:  1987-07

3.  Gas chromatographic determination of butoxyacetic acid in human blood after exposure to 2-butoxyethanol.

Authors:  G Johanson; S Johnsson
Journal:  Arch Toxicol       Date:  1991       Impact factor: 5.153

4.  An improved method for the determination in urine of alkoxyacetic acids.

Authors:  D Groeseneken; H Veulemans; R Masschelein; E Van Vlem
Journal:  Int Arch Occup Environ Health       Date:  1989       Impact factor: 3.015

5.  Inhalation toxicokinetics of butoxyethanol and its metabolite butoxyacetic acid in the male Sprague-Dawley rat.

Authors:  G Johanson
Journal:  Arch Toxicol       Date:  1994       Impact factor: 5.153

6.  Gas chromatographic determination of methoxyacetic and ethoxyacetic acid in urine.

Authors:  D Groeseneken; E van Vlem; H Veulemans; R Masschelein
Journal:  Br J Ind Med       Date:  1986-01

7.  2-Butoxyethanol autoprotection is due to resiliance of newly formed erythrocytes to hemolysis.

Authors:  D V Sivarao; H M Mehendale
Journal:  Arch Toxicol       Date:  1995       Impact factor: 5.153

8.  Urinary excretion of ethoxyacetic acid after experimental human exposure to ethylene glycol monoethyl ether.

Authors:  D Groeseneken; H Veulemans; R Masschelein
Journal:  Br J Ind Med       Date:  1986-09

9.  Analyses of ethylene glycol monoalkyl ethers and their proposed metabolites in blood and urine.

Authors:  A W Smallwood; K E DeBord; L K Lowry
Journal:  Environ Health Perspect       Date:  1984-08       Impact factor: 9.031

10.  Prediction of rodent carcinogenicity using the DEREK system for 30 chemicals currently being tested by the National Toxicology Program. The DEREK Collaborative Group.

Authors:  C A Marchant
Journal:  Environ Health Perspect       Date:  1996-10       Impact factor: 9.031
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