| Literature DB >> 5810049 |
Abstract
The influence of the size of the antigen in the polysaccharide-enhanced precipitin reaction was investigated. The experiments were carried out by addition of homologous antigens of different molecular sizes (the monomer, dimer and trimer of serum albumin and the monomer and dimer of immunoglobulin G) to the same preparation of antibody in the absence and presence of dextran. Dextran decreased the solubility of the immune complexes to a larger extent when the antigen size increased. This is in accord with the view that the polysaccharide effect is due to steric exclusion.Entities:
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Year: 1969 PMID: 5810049 PMCID: PMC1184807 DOI: 10.1042/bj1140145
Source DB: PubMed Journal: Biochem J ISSN: 0264-6021 Impact factor: 3.857