Literature DB >> 5808073

Correlation between growth inhibition and the binding of various penicillins and cephalosporins to Staphylococcus aureus.

J R Edwards, J T Park.   

Abstract

The concentration of penicillin (or cephalosporin) required to achieve a given rate of binding to Staphylococcus aureus H correlates well with that required for inhibition of growth. This result suggests that the irreversible binding of penicillins and cephalosporins to cells is responsible for their biological activity.

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Year:  1969        PMID: 5808073      PMCID: PMC250038          DOI: 10.1128/jb.99.2.459-462.1969

Source DB:  PubMed          Journal:  J Bacteriol        ISSN: 0021-9193            Impact factor:   3.490


  15 in total

1.  The site of action of penicillin: some properties of the penicillin-binding component of Staphylococcus aureus.

Authors:  P D COOPER
Journal:  J Gen Microbiol       Date:  1955-02

2.  The nature of the binding of penicillin by bacterial cells.

Authors:  S A Schepartz; M J Johnson
Journal:  J Bacteriol       Date:  1956-01       Impact factor: 3.490

3.  The association of the penicillin-binding component of Staphylococcus aureus with a lipid fraction.

Authors:  P D COOPER
Journal:  J Gen Microbiol       Date:  1954-04

4.  Properties of the penicillin binding component of Micrococcus pyogenes.

Authors:  J W DANIEL; M J JOHNSON
Journal:  J Bacteriol       Date:  1954-03       Impact factor: 3.490

5.  PENICILLIN UPTAKE BY BACTERIAL CELLS.

Authors:  E A Maass; M J Johnson
Journal:  J Bacteriol       Date:  1949-04       Impact factor: 3.490

6.  Glycopeptide transpeptidase and D-alanine carboxypeptidase: penicillin-sensitive enzymatic reactions.

Authors:  K Izaki; M Matsuhashi; J L Strominger
Journal:  Proc Natl Acad Sci U S A       Date:  1966-03       Impact factor: 11.205

7.  Penicillin: its basic site of action as an inhibitor of a peptide cross-linking reaction in cell wall mucopeptide synthesis.

Authors:  E M Wise; J T Park
Journal:  Proc Natl Acad Sci U S A       Date:  1965-07       Impact factor: 11.205

8.  Inhibition of the biosynthesis of cell-wall mucopeptides by the penicillins. A study of penicillin-sensitive and penicillin-resistant strains of Staphylococcus aureus.

Authors:  H J ROGERS; J JELJASZEWICZ
Journal:  Biochem J       Date:  1961-12       Impact factor: 3.857

9.  The binding of penicillin in relation to its cytotoxic action. II. The reactivity with penicillin of resistant variants of streptococci, pneumococci, and staphylococci.

Authors:  H EAGLE
Journal:  J Exp Med       Date:  1954-07-01       Impact factor: 14.307

10.  The binding of penicillin in relation to its cytotoxic action. I. Correlation between the penicillin sensitivity and combining activity of intact bacteria and cell-free extracts.

Authors:  H EAGLE
Journal:  J Exp Med       Date:  1954-03       Impact factor: 14.307

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  18 in total

1.  Comparison of the binding of penicillin G to staphylococcal L-form and its parent strain membranes.

Authors:  H Suginaka
Journal:  Antimicrob Agents Chemother       Date:  1976-03       Impact factor: 5.191

2.  Antagonism of the antibacterial action of some penicillins by other penicillins and cephalosporins.

Authors:  J F Acar; L D Sabath; P A Ruch
Journal:  J Clin Invest       Date:  1975-03       Impact factor: 14.808

3.  Effect of pH and human serum on the susceptibility of group D streptococci (Enterococci) to ampicillin in vitro.

Authors:  D N Gilbert; N Eubanks
Journal:  Antimicrob Agents Chemother       Date:  1975-04       Impact factor: 5.191

4.  Mechanism of synergistic action of a combination of ampicillin and dicloxacillin against a beta-lactamase-producing strain of Citrobacter freundii.

Authors:  J Mizoguchi; H Suginaka; S Kotani
Journal:  Antimicrob Agents Chemother       Date:  1979-10       Impact factor: 5.191

Review 5.  Interaction of penicillin with the bacterial cell: penicillin-binding proteins and penicillin-sensitive enzymes.

Authors:  P M Blumberg; J L Strominger
Journal:  Bacteriol Rev       Date:  1974-09

6.  Binding of radioactive benzylpenicillin to sporulating Bacillus cultures: chemistry and fluctuations in specific binding capacity.

Authors:  P J Lawrence; M Rogolsky; V T Hanh
Journal:  J Bacteriol       Date:  1971-11       Impact factor: 3.490

7.  Resistance to penicillin in mutants of a penicillinase-negative organism, Staphylococcus aureus H.

Authors:  J T Park; M E Griffith; I Stevenson
Journal:  J Bacteriol       Date:  1971-12       Impact factor: 3.490

8.  Altered penicillin-binding components in penicillin-resistant mutants of Bacillus subtilis.

Authors:  C E Buchanan; J L Strominger
Journal:  Proc Natl Acad Sci U S A       Date:  1976-06       Impact factor: 11.205

9.  Penicillin-resistant mechanisms in Pseudomonas aeruginosa: binding of penicillin to Pseudomonas aeruginosa KM 338.

Authors:  H Suginaka; A Ichikawa; S Kotani
Journal:  Antimicrob Agents Chemother       Date:  1975-05       Impact factor: 5.191

10.  Carbenicillin indanyl sodium, an orally active derivative of carbenicillin.

Authors:  A R English; J A Retsema; V A Ray; J E Lynch
Journal:  Antimicrob Agents Chemother       Date:  1972-03       Impact factor: 5.191

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