Literature DB >> 580509

The value of phenformin and ethyloestrenol in the prevention of deep venous thrombosis in patients undergoing surgery.

P Atkins, I K Brown, R J Downie, B G Haggart, J Littler, P M Robb, G J Santer, I Jones.   

Abstract

The effect of phenformin and ethyloestrenol on the incidence of post-operative deep venous thrombosis was studied in 314 surgical patients in a double-blind randomised trial. Although the laboratory tests suggested that the regime produced an increase in activators of the fibrinolytic system, the drugs used did not lower the incidence of post-operative deep venous thrombosis. Possible explanations of this paradox are advanced.

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Year:  1978        PMID: 580509

Source DB:  PubMed          Journal:  Thromb Haemost        ISSN: 0340-6245            Impact factor:   5.249


  2 in total

1.  Haemostatic changes in tall girls treated with high doses of ethinyloestradiol.

Authors:  W Muntean; M Borkenstein
Journal:  Eur J Pediatr       Date:  1980-09       Impact factor: 3.183

2.  Primary prophylaxis for venous thromboembolism in people undergoing major amputation of the lower extremity.

Authors:  David Rb Herlihy; Matthew Thomas; Quoc H Tran; Vikram Puttaswamy
Journal:  Cochrane Database Syst Rev       Date:  2020-07-21
  2 in total

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