| Literature DB >> 580440 |
S Aonuma, M Okabe, M Kawaguchi.
Abstract
The fertilization rate of mouse gametes in a Krebs-Ringer bicarbonate medium was 60%. The rate fell to 0% when 250 micron-ZnCl2 was added, but MgCl2, CaCl2, MnCl2, FeCl2, and CuCl2 (each at 250 micron) had no effect. The inhibitory effect of Zn2+ was not evident if the spermatozoa or eggs were preincubated with Zn2+ or if previously capacitated spermatozoa were used. The Zn2+ is thought to act by interference with capacitation.Entities:
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Year: 1978 PMID： 580440 DOI： 10.1530/jrf.0.0530179
Source DB: PubMed Journal: J Reprod Fertil ISSN： 0022-4251