Literature DB >> 5798315

Micelle formation between 5-hydroxytryptamine and adenosine triphosphate in platelet storage organelles.

K H Berneis, M Da Prada, A Pletscher.   

Abstract

As judged by analytical ultracentrifugation, 5-hydroxytryptamine and adenosine-5'-triphosphate form micelles in artificial mixtures and also in storage organelles containing 5-hydroxytryptamine of blood platelets of rabbits. Their average apparent molecular weights depend on the concentration and on the molar ratio of the two constituents. The 5-hydroxytryptamine and adenosine triphosphate of these 5-hydroxytryptamine organelles may be stored in vivo together as micelles with apparent molecular weights of several hundred thousands or more.

Entities:  

Mesh:

Substances:

Year:  1969        PMID: 5798315     DOI: 10.1126/science.165.3896.913

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  18 in total

1.  Evidence for control of serotonin secretion from human platelets by hydroxyl ion transport and osmotic lysis.

Authors:  H B Pollard; K Tack-Goldman; C J Pazoles; C E Creutz; N R Shulman
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

2.  Storage of biogenic amines in blood platelets and adrenal medulla. Lack of evidence for direct involvement of glycosaminoglycans.

Authors:  M Da Prada; K Von Berlepsch; A Pletscher
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1972       Impact factor: 3.000

3.  Interaction of aggregated catecholamines and nucleotides with intragranular proteins.

Authors:  K H Berneis; U Goetz; M Da Prada; A Pletscher
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1973       Impact factor: 3.000

4.  Abnormalities of 5-hydroxytryptamine uptake and binding by blood platelets from children with Down's syndrome.

Authors:  D J Boullin; R A O'Brien
Journal:  J Physiol       Date:  1971-01       Impact factor: 5.182

5.  Storage of ATP and 5-hydroxytryptamine in blood platelets of guinea-pigs.

Authors:  M Da Prada; A Pletscher; J P Tranzer
Journal:  J Physiol       Date:  1971-09       Impact factor: 5.182

6.  Uptake and loss of 14 C-dopamine by platelets from children with infantile autism.

Authors:  D J Boullin; R A O'Brien
Journal:  J Autism Child Schizophr       Date:  1972 Jan-Mar

7.  Identification of guanosine 5'-triphosphate and uridine 5'-triphosphate in subcellular monamine-storage organelles.

Authors:  M da Prada; A Pletscher
Journal:  Biochem J       Date:  1970-08       Impact factor: 3.857

8.  Studies on human platelet gangliosides.

Authors:  A J Marcus; H L Ullman; L B Safier
Journal:  J Clin Invest       Date:  1972-10       Impact factor: 14.808

9.  Phase separation in solutions of noradrenaline and adenosine triphosphate: influence of bivalent cations and drugs.

Authors:  K H Berneis; A Pletscher; M Da Prada
Journal:  Br J Pharmacol       Date:  1970-06       Impact factor: 8.739

10.  Accumulation of quinidine by human blood platelets: effects on platelet ultrastructure and 5-hydroxytryptamine.

Authors:  D J Boullin; R A O'Brien
Journal:  Br J Pharmacol       Date:  1971-05       Impact factor: 8.739

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.