Literature DB >> 5797529

Bacterial 7-dehydroxylation of cholic acid and allocholic acid.

V Bokkenheuser, T Hoshita, E H Mosbach.   

Abstract

An obligate anaerobic organism capable of dehydroxylating cholic acid to deoxycholic acid and allocholic acid to allodeoxycholic acid was isolated from feces of the rabbit. It was a member of the bacteroides group (Gram-variable, nonsporulating anaerobes). The growth of the organism was inhibited by neomycin, 10-20 micro g/ml. The existence of this organism affords a satisfactory explanation for the development of gallstones in the cholestanol-fed rabbit and for their absence in rabbits simultaneously treated with neomycin.

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Year:  1969        PMID: 5797529

Source DB:  PubMed          Journal:  J Lipid Res        ISSN: 0022-2275            Impact factor:   5.922


  8 in total

1.  Assessment of fecal bacteria with bile acid 7 alpha-dehydroxylating activity for the presence of bai-like genes.

Authors:  K C Doerner; F Takamine; C P LaVoie; D H Mallonee; P B Hylemon
Journal:  Appl Environ Microbiol       Date:  1997-03       Impact factor: 4.792

2.  Isolation and characterization of human fecal bacteria capable of 21-dehydroxylating corticoids.

Authors:  V D Bokkenheuser; J Winter; P Dehazya; W G Kelly
Journal:  Appl Environ Microbiol       Date:  1977-11       Impact factor: 4.792

3.  7 alpha-Dehydroxylation of bile acids by resting cells of an unidentified, gram-positive, nonsporeforming anaerobic bacterium.

Authors:  N Masuda; H Oda
Journal:  Appl Environ Microbiol       Date:  1983-02       Impact factor: 4.792

4.  Metabolism of deoxycorticosterone by human fecal flora.

Authors:  V D Bokkenheuser; J B Suzuki; S B Polovsky; J Winter; W G Kelly
Journal:  Appl Microbiol       Date:  1975-07

5.  7 alpha-Dehydroxylation of bile acids by resting cells of a Eubacterium lentum-like intestinal anaerobe, strain c-25.

Authors:  N Masuda; H Oda; S Hirano; M Masuda; H Tanaka
Journal:  Appl Environ Microbiol       Date:  1984-04       Impact factor: 4.792

6.  Oleic acid-induced cholelithiasis in rabbits. Changes in bile composition and gallbladder morphology.

Authors:  S P Lee; C Tasman-Jones; V Carlisle
Journal:  Am J Pathol       Date:  1986-07       Impact factor: 4.307

7.  Isolation and characterization of thirteen intestinal microorganisms capable of 7 alpha-dehydroxylating bile acids.

Authors:  S Hirano; R Nakama; M Tamaki; N Masuda; H Oda
Journal:  Appl Environ Microbiol       Date:  1981-03       Impact factor: 4.792

8.  Impact of Deoxycholic Acid on Oesophageal Adenocarcinoma Invasion: Effect on Matrix Metalloproteinases.

Authors:  Fran Quilty; Anne-Marie Byrne; John Aird; Sheeren El Mashad; Adolfo Parra-Blanco; Aideen Long; John F Gilmer; Carlos Medina
Journal:  Int J Mol Sci       Date:  2020-10-28       Impact factor: 5.923

  8 in total

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